2. Gene
  3. C1QTNF2 - C1q and TNF related 2 Gene

C1QTNF2 - C1q and TNF related 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：C1q 和 TNF 相关 2

种属: Homo sapiens

同用名: CTRP2; zacrp2

基因 ID: 114898 | 基因类型: protein coding

关于 C1QTNF2

Cytogenetic location: 5q33.3 Genomic coordinates (GRCh38): 5:160,347,754-160,370,626 (from NCBI)

This gene has 2 transcripts (splice variants), 188 orthologues and 23 paralogues. Broad expression in testis (RPKM 1.3), lung (RPKM 1.2) and 23 other tissues.

功能概要

预测具有相同的蛋白质结合活性和信号受体结合活性。预计参与脂质代谢过程的调节。预计在 MAPK 级联的正调控上游或正调控内起作用；积极调节葡萄糖输入；和小分子代谢过程的正调控。预计位于细胞外空间。预计是含蛋白质复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable identical protein binding activity and signaling receptor binding activity. Predicted to be involved in regulation of lipid metabolic process. Predicted to act upstream of or within positive regulation of MAPK cascade; positive regulation of glucose import; and positive regulation of small molecule metabolic process. Predicted to be located in extracellular space. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

C1QTNF2 基因产物(2)

mRNA Protein Name
NM_001366504.1 NP_001353433.1 complement C1q tumor necrosis factor-related protein 2 isoform 2 precursor
NM_031908.6 NP_114114.3 complement C1q tumor necrosis factor-related protein 2 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

C1QTNF2 蛋白结构

Collagen

Collagen: Collagen triple helix repeat (20 copies) (85 - 143)

Collagen

Collagen: Collagen triple helix repeat (20 copies) (127 - 184)

C1q

C1q: C1q domain (196 - 320)

  • 0
  • 100
  • 200
  • 300
  • 330 a.a.
蛋白主名 其他名称

complement C1q tumor necrosis factor-related protein 2

C1q and tumor necrosis factor related protein 2

C1QTNF2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
C1QTNF2 Q9BXJ5 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Array
25416956
种属内
C1QTNF2 Q9BXJ5 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
25416956
种属内
C1QTNF2 Q9BXJ5 TIMM8A Homo sapiens O60220
Y2H Array
32296183
种属内
C1QTNF2 Q9BXJ5 TIMM8A Homo sapiens O60220
Y2H Prey Pooling
32296183
种属内
C1QTNF2 Q9BXJ5 HPCA Homo sapiens P84074
Y2H Prey Pooling
32296183
种属内
C1QTNF2 Q9BXJ5 HPCA Homo sapiens P84074
Y2H Array
32296183
种属内
C1QTNF2 Q9BXJ5 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
种属内
C1QTNF2 Q9BXJ5 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
25416956
种属内
C1QTNF2 Q9BXJ5 KLHL12 Homo sapiens Q53G59
Y2H Array
32296183
种属内
C1QTNF2 Q9BXJ5 KLHL12 Homo sapiens Q53G59
Y2H Prey Pooling
25416956
种属内
C1QTNF2 Q9BXJ5 KLHL12 Homo sapiens Q53G59
Y2H Array
25416956
种属内
C1QTNF2 Q9BXJ5 KLHL12 Homo sapiens Q53G59
Y2H Prey Pooling
32296183
种属内
C1QTNF2 Q9BXJ5 CHIC2 Homo sapiens Q9UKJ5
Validated Y2H
32296183
种属内
C1QTNF2 Q9BXJ5 HPCAL1 Homo sapiens P37235
Y2H Array
32296183
种属内
C1QTNF2 Q9BXJ5 HPCAL1 Homo sapiens P37235
Y2H Prey Pooling
32296183
种属内
C1QTNF2 Q9BXJ5 HPCAL1 Homo sapiens P37235
Y2H Array
25416956
种属内
C1QTNF2 Q9BXJ5 NCALD Homo sapiens P61601
MAPPIT
25416956
种属内
C1QTNF2 Q9BXJ5 NCALD Homo sapiens P61601
MAPPIT
32296183
种属内
C1QTNF2 Q9BXJ5 NCALD Homo sapiens P61601
Y2H Prey Pooling
25416956
种属内
C1QTNF2 Q9BXJ5 KCNIP3 Homo sapiens Q9Y2W7
Validated Y2H
32296183
种属内
C1QTNF2 Q9BXJ5 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
种属内
C1QTNF2 Q9BXJ5 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属内
C1QTNF2 Q9BXJ5 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属内
C1QTNF2 Q9BXJ5 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinitis Pigmentosa 19

RP19

Retinitis Pigmentosa-19

Retinitis Pigmentosa, Type 19
Late-Onset Retinal Degeneration

LORD

Retinal Degeneration, Late-Onset, Autosomal Dominant

Autosomal Dominant Late-Onset Retinal Degeneration

Pigmentary Retinopathy

Retinal Degeneration, Late-Onset

Retinitis Pigmentosa
Vertigo, Benign Recurrent

Benign Paroxysmal Positional Vertigo

Bppv

Vestibulopathy, Familial

BRV

Vertigo, Benign Paroxysmal Positional

Benign Paroxysmal Positional Nystagmus

Benign Recurrent Vertigo

Familial Benign Recurrent Vertigo

Familial Vestibulopathy

Benign Paroxysmal Nystagmus

Bppv - [Benign Positional Paroxysmal Vertigo]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01728 C1QTNF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris C1QTNF2 VGNC VGNC:38583
Felis catus C1QTNF2 VGNC VGNC:102169
Rattus norvegicus C1QTNF2 RGD RGD:1561041
Macaca mulatta C1QTNF2 VGNC VGNC:70312
Mus musculus C1QTNF2 MGD MGI:1916433
Bos taurus C1QTNF2 VGNC VGNC:26624
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