1. Gene
  2. F11r - F11 receptor Gene

F11r - F11 receptor Gene

种属: Rattus norvegicus

同用名: Jam1

基因 ID: 116479 | 基因类型: protein coding

关于 F11r

功能概要

Predicted to enable PDZ domain binding activity; Integrin binding activity; and protein homodimerization activity. Involved in cell differentiation; positive regulation of blood pressure; and response to radiation. Located in cytoplasmic vesicle and slit diaphragm. Biomarker of hypertension; peptic esophagitis; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor). [provided by Alliance of Genome Resources, Apr 2022]

F11r 基因产物(2)

mRNA Protein Name
NM_053796.1 NP_446248.1 junctional adhesion molecule A precursor
NM_053796.1 NP_446248.1 junctional adhesion molecule A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16617054 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell differentiation IEP
IEP: 通过表达模式推断
18506084 RGD
involved in positive regulation of blood pressure IDA
IDA: 通过直接分析推断
17420334 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
18506084 RGD
located in slit diaphragm IDA
IDA: 通过直接分析推断
19478094 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

junctional adhesion molecule A

JAM-1

JAM-A

junctional adhesion molecule 1

重组 F11r 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73853 JAM-A/CD321 Protein, Rat (HEK293, His) Q9JHY1 (K27-G238) ≥95%
HY-P73854 JAM-A/CD321 Protein, Rat (HEK293, Fc) Q9JHY1 (K27-G238) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F11r NCBI NCBI:50848
Mus musculus F11r NCBI NCBI:16456