1. Gene
  2. F11r - F11 receptor Gene

F11r - F11 receptor Gene

种属: Mus musculus

同用名: JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; 9130004G24

基因 ID: 16456 | 基因类型: protein coding

关于 F11r

功能概要

Predicted to enable PDZ domain binding activity; Integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor). [provided by Alliance of Genome Resources, Apr 2022]

F11r 基因产物(1)

mRNA Protein Name
NM_172647.2 NP_766235.1 junctional adhesion molecule A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11689568 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
15494378 MGI
acts upstream of or within epithelial cell differentiation IDA
IDA: 通过直接分析推断
15494378 MGI
involved in intestinal absorption IMP
IMP: 通过突变表型推断
23885123 MGI
involved in regulation of cytokine production IMP
IMP: 通过突变表型推断
18514073 MGI
involved in regulation of membrane permeability IMP
IMP: 通过突变表型推断
23885123 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in bicellular tight junction IMP
IMP: 通过突变表型推断
15494378 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

junctional adhesion molecule A

BV11 antigen

F11 receptor/F11R

junction cell adhesion molecule A

junction cell adhesion molecule1

junctional adhesion molecule 1

重组 F11r 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73855 JAM-A/CD321 Protein, Mouse (HEK293, Fc) O88792 (K27-A242) ≥95%
HY-P78322 JAM-A/CD321 Protein, Mouse (HEK293, His) O88792 (K27-G238) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F11r NCBI NCBI:50848
Rattus norvegicus F11r NCBI NCBI:116479