1. Gene
  2. Khdrbs1 - KH RNA binding domain containing, signal transduction associated 1 Gene

Khdrbs1 - KH RNA binding domain containing, signal transduction associated 1 Gene

种属: Rattus norvegicus

同用名: P62; Sam68

基因 ID: 117268 | 基因类型: protein coding

关于 Khdrbs1

功能概要

Enables SH3 domain binding activity and identical protein binding activity. Involved in cell surface receptor signaling pathway; regulation of alternative mRNA splicing, via spliceosome; and spermatogenesis. Located in cytoplasm; membrane; and nucleus. Part of Grb2-Sos complex. Orthologous to human KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Khdrbs1 基因产物(1)

mRNA Protein Name
NM_130405.2 NP_569089.1 KH domain-containing, RNA-binding, signal transduction-associated protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH3 domain binding IDA
IDA: 通过直接分析推断
12112020 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15345239 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10437794 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
12112020 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
10437794 RGD
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: 通过直接分析推断
15345239 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
10332027 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Grb2-Sos complex IDA
IDA: 通过直接分析推断
12112020 RGD
located in nucleus IDA
IDA: 通过直接分析推断
10332027 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

KH domain-containing, RNA-binding, signal transduction-associated protein 1

GAP-associated tyrosine phosphoprotein p62

KH domain containing, RNA binding, signal transduction associated 1

KH domain-containing, RNA-binding, signal transduction-associated protein 1-like

p21 Ras GTPase-activating protein-associated p62

p68

src a

Khdrbs1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra Khdrbs1 Q91V33 Pik3r1 Rattus norvegicus Q63787
CoIP
10437794
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Khdrbs1 NCBI NCBI:10657