2. Gene
  3. Bid - BH3 interacting domain death agonist Gene

Bid - BH3 interacting domain death agonist Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2700049M22Rik

基因 ID: 12122 | 基因类型: protein coding

关于 Bid

功能概要

Enables ubiquitin protein Ligase binding activity. Involved in positive regulation of cellular component organization; protein-containing complex assembly; and release of cytochrome c from mitochondria. Acts upstream of or within several processes, including apoptotic signaling pathway; hepatocyte apoptotic process; and regulation of apoptotic process. Located in cytosol; membrane; and mitochondrion. Is integral component of mitochondrial membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human BID (BH3 interacting domain death agonist). [provided by Alliance of Genome Resources, Apr 2022]

Bid 基因产物(1)

mRNA Protein Name
NM_007544.4 NP_031570.2 BH3-interacting domain death agonist
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
8918887 MGI
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
20392206 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
12011074 MGI
acts upstream of or within extrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
10476969 MGI
acts upstream of or within hepatocyte apoptotic process IGI
IGI: 通过遗传相互作用推断
20436477 MGI
acts upstream of or within mitochondrial ATP synthesis coupled electron transport IMP
IMP: 通过突变表型推断
26219591 MGI
acts upstream of or within mitochondrial outer membrane permeabilization IGI
IGI: 通过遗传相互作用推断
20436477 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: 通过突变表型推断
26219591 MGI
acts upstream of or within positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
8918887 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IDA
IDA: 通过直接分析推断
8918887 MGI
acts upstream of or within positive regulation of fibroblast apoptotic process IDA
IDA: 通过直接分析推断
8918887 MGI
acts upstream of or within positive regulation of mitochondrial membrane potential IMP
IMP: 通过突变表型推断
26219591 MGI
involved in positive regulation of protein-containing complex assembly IDA
IDA: 通过直接分析推断
20850011 MGI
involved in positive regulation of release of cytochrome c from mitochondria IGI
IGI: 通过遗传相互作用推断
10950869 MGI
acts upstream of or within protein targeting to mitochondrion IMP
IMP: 通过突变表型推断
11369777 MGI
involved in protein-containing complex assembly IDA
IDA: 通过直接分析推断
10950869 MGI
acts upstream of or within regulation of G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
15855651 MGI
acts upstream of or within regulation of T cell proliferation IMP
IMP: 通过突变表型推断
15855651 MGI
acts upstream of or within regulation of apoptotic process IGI
IGI: 通过遗传相互作用推断
8918887 MGI
acts upstream of or within regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
15855651 MGI
acts upstream of or within regulation of mitochondrial membrane permeability involved in apoptotic process IGI
IGI: 通过遗传相互作用推断
14963330 MGI
involved in release of cytochrome c from mitochondria IDA
IDA: 通过直接分析推断
18084238 MGI
acts upstream of or within release of cytochrome c from mitochondria IMP
IMP: 通过突变表型推断
11369777 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
8918887 MGI
located in membrane IDA
IDA: 通过直接分析推断
8918887 MGI
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
10950869 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
11369777 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

BH3-interacting domain death agonist

p22 BID

重组 Bid 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72852 BID Protein, Mouse (His-GST) EDK99650.1 (M12-D206) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0493 Niflumic acid Inhibitor 99.88% 否
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-10510 BI-D1870 99.72% 否
HY-103661 BI-6C9 Inhibitor 98.47% 否
HY-18601 (±)-BI-D Inhibitor 98.06% 否
HY-123244 YC137 / 否
HY-162642 Bfl-1-IN-3 Inhibitor / 否
HY-P10614 Bid BH3 peptide / 否
HY-P5325 Bid BH3 (80-99) / 否
HY-P5325F Bid BH3 (80-99), FAM labeled / 否
HY-P5327 r8 Bid BH3 / 否
HY-RS01502 BID Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-121200 Azadirone / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bid NCBI NCBI:637
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