2. Gene
  3. C1qa - complement component 1, q subcomponent, alpha polypeptide Gene

C1qa - complement component 1, q subcomponent, alpha polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: C1q; Adic

基因 ID: 12259 | 基因类型: protein coding

关于 C1qa

功能概要

Involved in several processes, including complement-mediated synapse pruning; microglial cell activation; and nervous system development. Acts upstream of or within complement activation, classical pathway. Located in postsynapse. Is expressed in brain; foot; genitourinary system; and pancreas. Used to study epilepsy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in glomerulonephritis. Orthologous to human C1QA (complement C1q A chain). [provided by Alliance of Genome Resources, Apr 2022]

C1qa 基因产物(1)

mRNA Protein Name
NM_007572.2 NP_031598.2 complement C1q subcomponent subunit A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22682250 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in astrocyte activation IGI
IGI: 通过遗传相互作用推断
15269255 MGI
acts upstream of or within complement activation, classical pathway IMP
IMP: 通过突变表型推断
11901193 MGI
involved in complement-mediated synapse pruning IMP
IMP: 通过突变表型推断
18083105 MGI
involved in microglial cell activation IGI
IGI: 通过遗传相互作用推断
15269255 MGI
involved in neuron remodeling IMP
IMP: 通过突变表型推断
18083105 MGI
involved in synapse organization IGI
IGI: 通过遗传相互作用推断
27033548 MGI
involved in synapse pruning IGI
IGI: 通过遗传相互作用推断
27033548 MGI
involved in vertebrate eye-specific patterning IMP
IMP: 通过突变表型推断
18083105 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in extrinsic component of postsynaptic membrane IDA
IDA: 通过直接分析推断
23946404 MGI
is active in extrinsic component of presynaptic membrane IDA
IDA: 通过直接分析推断
23946404 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23946404 MGI
located in postsynapse IGI
IGI: 通过遗传相互作用推断
27033548 MGI
located in synapse IDA
IDA: 通过直接分析推断
18083105 MGI
located in synapse IGI
IGI: 通过遗传相互作用推断
18083105 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complement C1q subcomponent subunit A

adiponectin c

重组 C1qa 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71718 C1QA Protein, Mouse (P.pastoris, His) P98086 (E23-A245) ≥95%
HY-P72108 C1QA Protein, Mouse (His-SUMO) P98086 (E23-A245) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01718 C1QA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens C1qa NCBI NCBI:712
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