2. Gene
  3. Dct - dopachrome tautomerase Gene

Dct - dopachrome tautomerase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: DT; slt; TRP2; TRP-2; Tyrp2; slaty; Tyrp-2

基因 ID: 13190 | 基因类型: protein coding

关于 Dct

功能概要

Enables dopachrome isomerase activity. Involved in melanin biosynthetic process from tyrosine. Acts upstream of or within several processes, including developmental pigmentation; generation of neurons; and melanin biosynthetic process. Located in cytosol and melanosome. Is expressed in several structures, including embryo ectoderm; embryo mesenchyme; integumental system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in oculocutaneous albinism. Orthologous to human DCT (dopachrome tautomerase). [provided by Alliance of Genome Resources, Apr 2022]

Dct 基因产物(1)

mRNA Protein Name
NM_010024.3 NP_034154.2 L-dopachrome tautomerase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dopachrome isomerase activity IDA
IDA: 通过直接分析推断
2169885 MGI
enables dopachrome isomerase activity IMP
IMP: 通过突变表型推断
1537334 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell development IMP
IMP: 通过突变表型推断
15060160 MGI
acts upstream of or within developmental pigmentation IMP
IMP: 通过突变表型推断
15060160 MGI
acts upstream of or within melanin biosynthetic process IMP
IMP: 通过突变表型推断
7665913 MGI
involved in melanin biosynthetic process from tyrosine IDA
IDA: 通过直接分析推断
2169885 MGI
involved in melanin biosynthetic process from tyrosine IMP
IMP: 通过突变表型推断
33100333 MGI
acts upstream of neuroblast proliferation IMP
IMP: 通过突变表型推断
16857183 MGI
acts upstream of or within pigmentation IMP
IMP: 通过突变表型推断
1537334 MGI
acts upstream of or within positive regulation of neuroblast proliferation IMP
IMP: 通过突变表型推断
16857183 MGI
acts upstream of or within ventricular zone neuroblast division IMP
IMP: 通过突变表型推断
16857183 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
21610032 MGI
located in cytosol IDA
IDA: 通过直接分析推断
2169885 MGI
located in melanosome IDA
IDA: 通过直接分析推断
2169885 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

L-dopachrome tautomerase

DOPAchrome conversion factor

DOPAchrome isomerase

DOPAchrome oxidoreductase

L-dopachrome Delta-isomerase

SLATY locus protein

tyrosinase-related protein 2

重组 Dct 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72169 DCT Protein, Mouse (His-SUMO) P29812 (Q24-S472) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-113042 Prostaglandin B2 ≥99.0% 否
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101400A Deoxycytidine triphosphate (trisodium) solution (100mM) Activator 99.46% 否
HY-132142 5-Propargylamino-dCTP Chemical ≥98.0% 否
HY-W013178 DCTA monohydrate ≥98.0% 否
HY-132146A 5-Propargylamino-ddCTP (trisodium) solution (25mM) Chemical ≥99.0% 否
HY-138561C EFdA-TP tetralithium Inhibitor 96.23% 否
HY-138561A EFdA-TP tetraammonium Inhibitor 98.03% 否
HY-138561B EFdA-TP tetrasodium Inhibitor 95.18% 否
HY-N2983 Cajanin Inhibitor 99.96% 否
HY-138561 EFdA-TP Inhibitor / 否
HY-143869 HPK1-IN-28 Inhibitor / 否
HY-143870 HPK1-IN-29 Inhibitor / 否
HY-148412 Monarsen Inhibitor / 否
HY-RS03591 DCT Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dct NCBI NCBI:1638
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