2. Gene
  3. ZFP42 - ZFP42 zinc finger protein Gene

ZFP42 - ZFP42 zinc finger protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ZFP42 锌指蛋白

种属: Homo sapiens

同用名: REX1; REX-1; ZNF754; zfp-42

基因 ID: 132625 | 基因类型: protein coding

关于 ZFP42

Cytogenetic location: 4q35.2 Genomic coordinates (GRCh38): 4:187,995,771-188,005,246 (from NCBI)

This gene has 3 transcripts (splice variants), 75 orthologues and 2 paralogues. Biased expression in testis (RPKM 1.0), placenta (RPKM 0.5) and 1 other tissue.

功能概要

启用序列特异性双链 DNA 结合活性。参与女性性腺发育和男性性腺发育。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables sequence-specific double-stranded DNA binding activity. Involved in female gonad development and male gonad development. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZFP42 基因产物(2)

mRNA Protein Name
NM_001304358.2 NP_001291287.1 zinc finger protein 42 homolog
NM_174900.5 NP_777560.2 zinc finger protein 42 homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female gonad development IEP
IEP: 通过表达模式推断
18281244 GOA
involved in male gonad development IEP
IEP: 通过表达模式推断
18281244 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
16344273 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZFP42 蛋白结构

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (189 - 212)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (232 - 257)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (261 - 286)

  • 0
  • 100
  • 200
  • 310 a.a.
蛋白主名 其他名称

zinc finger protein 42 homolog

REX1 transcription factor

ZFP42 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZFP42 Q96MM3 LHX2 Homo sapiens P50458
Y2H Array
32296183
Intra ZFP42 Q96MM3 LHX2 Homo sapiens P50458
Y2H Prey Pooling
32296183
Intra ZFP42 Q96MM3 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra ZFP42 Q96MM3 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra ZFP42 Q96MM3 RNF4 Homo sapiens P78317
Y2H Array
32296183
Intra ZFP42 Q96MM3 RNF4 Homo sapiens P78317
Y2H Prey Pooling
32296183
Intra ZFP42 Q96MM3 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra ZFP42 Q96MM3 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Intra ZFP42 Q96MM3 SUMO1 Homo sapiens P63165
Y2H Array
32296183
Intra ZFP42 Q96MM3 SUMO1 Homo sapiens P63165
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Inflammatory Bowel Disease 7

IBD7
Germ Cell And Embryonal Cancer

Germ Cell And Embryonal Neoplasm
Spermatocytoma

Spermatocytic Seminoma
Arthrogryposis, Distal, Type 1a

Distal Arthrogryposis Type 1

Digitotalar Dysmorphism

DA1A

Da1

Amcd1

Arthrogryposis, Distal, Type 2b4

Distal Arthrogryposis Type 1a

Arthrogryposis, Distal, Type 1

Arthrogryposis Multiplex Congenita Distal Type 1

Arthrogryposis Multiplex Congenita, Distal Type 1

Arthrogryposis Multiplex Congenita, Distal, Type I

Distal Arthrogryposis Type 1b

Arthrogryposis, Distal, 1a

Amc

Arthrogryposis Multiplex Congenita

Arthrogryposis, Distal, 2b4

DA2B4

Arthrogryposis Multiplex Congenita, Distal, Type 1

Arthrogryposis
Germ Cell Cancer

Malignant Germ Cell Tumor

Neoplasms, Germ Cell And Embryonal

Germ Cell Neoplasm

Germ Cell Tumour

Malignant Tumor Of The Germ Cell

Neoplasms Germ Cell

Malignant Germ Cell Neoplasm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16043 ZFP42 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ZFP42 MGD MGI:99187
Macaca mulatta ZFP42 VGNC VGNC:107210
Rattus norvegicus ZFP42 RGD RGD:2319133
Canis familiaris ZFP42 VGNC VGNC:53510
Felis catus ZFP42 VGNC VGNC:107479
Bos taurus ZFP42 VGNC VGNC:37164
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