2. Gene
  3. MYO3B - myosin IIIB Gene

MYO3B - myosin IIIB Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肌球蛋白 IIIB

种属: Homo sapiens

基因 ID: 140469 | 基因类型: protein coding

关于 MYO3B

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:170,178,147-170,655,167 (from NCBI)

This gene has 9 transcripts (splice variants), 187 orthologues and 43 paralogues. Biased expression in kidney (RPKM 2.4), urinary bladder (RPKM 2.3) and 4 other tissues.

功能概要

该基因编码 III 类肌球蛋白之一。肌球蛋白是 ATP 酶，由肌动蛋白激活，在细胞中沿着肌动蛋白丝移动。这类肌球蛋白的特征在于氨基末端激酶结构域，并显示存在于光感受器中。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2014 年 3 月]

This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]

MYO3B 基因产物(2)

mRNA Protein Name
NM_001083615.4 NP_001077084.2 myosin-IIIb isoform 1
NM_138995.5 NP_620482.3 myosin-IIIb isoform 2

MYO3B 蛋白结构

Pkinase

Pkinase: Protein kinase domain (27 - 293)

Myosin_head

Myosin_head: Myosin head (motor domain) (346 - 1046)

IQ

IQ: IQ calmodulin-binding motif (1089 - 1108)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1341 a.a.
蛋白主名 其他名称

myosin-IIIb

MYO3B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MYO3B Q8WXR4 HSP90AB1 Homo sapiens P08238
Pull Down
32707033
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Deafness, Autosomal Recessive 30

DFNB30

Autosomal Recessive Nonsyndromic Deafness 30

Autosomal Recessive Deafness 30

Deafness, Autosomal Recessive, 30

Deafness, Autosomal Recessive, Type 30
Entropion
Autosomal Recessive Nonsyndromic Deafness

Deafness, Autosomal Recessive, Nonsyndromic
Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08945 MYO3B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MYO3B VGNC VGNC:74961
Mus musculus MYO3B MGD MGI:2448580
Rattus norvegicus MYO3B RGD RGD:1560313
Canis familiaris MYO3B VGNC VGNC:49692
Felis catus MYO3B VGNC VGNC:63689
Bos taurus MYO3B VGNC VGNC:31825
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