1. Gene
  2. F3 - coagulation factor III Gene

F3 - coagulation factor III Gene

种属: Mus musculus

同用名: TF; Cf3; Cf-3; CD142

基因 ID: 14066 | 基因类型: protein coding

关于 F3

功能概要

This gene encodes a membrane-bound glycoprotein that forms the primary physiological initiator of the blood coagulation process following vascular damage. The encoded protein binds to coagulation Factor VIIa and the ensuing complex catalyzes the proteolytic activation of coagulation factors IX and X. Mice lacking encoded protein die in utero resulting from massive hemorrhaging in both extraembryonic and embryonic vessels. A severe deficiency of the encoded protein in mice results in impaired uterine homeostasis, shorter life spans due to spontaneous fatal hemorrhages and cardiac fibrosis. [provided by RefSeq, Aug 2015]

F3 基因产物(1)

mRNA Protein Name
NM_010171.3 NP_034301.3 tissue factor precursor
蛋白主名 其他名称

tissue factor

重组 F3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71127 Tissue Factor Protein, Mouse (HEK293, His) P20352 (A29-E251) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F3 NCBI NCBI:2152
Canis familiaris F3 NCBI NCBI:490153
Macaca fascicularis F3 NCBI NCBI:102131431
Leporidae F3 NCBI
Rattus norvegicus F3 NCBI NCBI:25584
Macaca mulatta F3 NCBI NCBI:714456