2. Gene
  3. Gh - growth hormone Gene

Gh - growth hormone Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gh1; Ghb1

基因 ID: 14599 | 基因类型: protein coding

关于 Gh

功能概要

Enables growth hormone receptor binding activity. Acts upstream of or within cellular response to Insulin stimulus; regulation of growth; and response to food. Located in several cellular components, including extracellular space; secretory granule; and trans-Golgi network. Is expressed in brain; early conceptus; gut; hemolymphoid system; and male reproductive system. Used to study isolated growth hormone deficiency type II. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); autoimmune disease of endocrine system (multiple); diabetic retinopathy; isolated growth hormone deficiency (multiple); and progeria. Orthologous to several human genes including GH1 (growth hormone 1). [provided by Alliance of Genome Resources, Apr 2022]

Gh 基因产物(1)

mRNA Protein Name
NM_008117.3 NP_032143.1 somatotropin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth hormone receptor binding IPI
IPI: 通过物理相互作用推断
10556780 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to insulin stimulus IDA
IDA: 通过直接分析推断
16513828 MGI
acts upstream of or within positive regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
16467156 MGI
acts upstream of or within response to food IDA
IDA: 通过直接分析推断
16513828 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
7664670 MGI
located in nucleus IDA
IDA: 通过直接分析推断
9144201 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9144201 MGI
located in secretory granule IDA
IDA: 通过直接分析推断
1329576 MGI
located in trans-Golgi network IDA
IDA: 通过直接分析推断
9144201 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

somatotropin

growth hormone b1

重组 Gh 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70261 GH/Somatotropin Protein, Mouse P06880 (F27-F216) ≥95%

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-16381A Pasireotide acetate Agonist 99.82% 是
HY-16381 Pasireotide Agonist 99.88% 否
HY-108905 Mecasermin / 否
HY-14820 Macimorelin Agonist / 否
HY-14820A Macimorelin acetate Agonist 98.96% 是
Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-109155 Paltusotine Agonist 99.52% Phase 3
HY-50844 Ibutamoren Mesylate Agonist 99.86% Phase 2
HY-P0024 Veldoreotide Activator / Phase 2
HY-153485 Cimdelirsen Inhibitor / Phase 2
HY-153485A Cimdelirsen sodium Inhibitor / Phase 2
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99900 Sevirumab Inhibitor / Phase 3
Pre-clinical Phase
生物活性分子 (43)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-134541 SM-102 99.90% 否
HY-13913 NS-398 Inhibitor 99.72% 否
HY-D1599 Rhodamine 6G hydrazide 98.05% 否
HY-10957 L-692429 Agonist 99.90% 否
HY-P0089A Human growth hormone-releasing factor TFA 99.66% 否
HY-101422 GAL-021 Inhibitor 99.93% 否
HY-139431 NAG-thiazoline Inhibitor 98.08% 否
HY-115661 Bisdionin C Inhibitor 98.97% 否
HY-149902 USP8-IN-3 Inhibitor 99.17% 否
HY-50760 L-692585 Agonist 99.32% 否
HY-P0024A Veldoreotide TFA Agonist 98.37% 否
HY-P1777 IGF-I (24-41) 99.11% 否
HY-P5189A His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA 99.31% 否
HY-107678 SEN12333 Agonist 98.45% 否
HY-D1515 FM1-84 98.92% 否
HY-E70033 D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) / 否
HY-P0089 Human growth hormone-releasing factor / 否
HY-101422A GAL-021 sulfate Inhibitor / 否
HY-10199A Ibutamoren Agonist / 否
HY-103540 Tabimorelin hemifumarate Inhibitor / 否
HY-110161 sst2 Receptor agonist-1 Agonist / 否
HY-113906A (αR,8aS)-GSK1614343 Antagonist 99.40% 否
HY-117584 L-163255 free base / 否
HY-117931 NS004 Activator / 否
HY-121580 Tabimorelin Inhibitor / 否
HY-134541A SM-102 (Excipient) / 否
HY-147666 α-Synuclein inhibitor 4 Inhibitor / 否
HY-E70105 α-Xylosidase / 否
HY-E70107 Cellobiohydrolase I / 否
HY-E70111 Endo-1,5-α-arabinanase / 否
HY-E70316 Chimax-O / 否
HY-P1139 Cortistatin-8 Antagonist / 否
HY-P1773A IGF-I (30-41) (TFA) / 否
HY-P1777A IGF-I (24-41) (TFA) / 否
HY-P3169 a-Helical Corticotropin Releasing Factor (9-41) Antagonist / 否
HY-P3595 GHRF, porcine / 否
HY-P3607 GHRF, bovine Activator / 否
HY-RS05408 GH1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05409 GH2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-109155A Paltusotine hydrochloride Agonist / 否
HY-10957A L-692429 hydrochloride Agonist / 否
HY-116959 SM-130686 / 否
HY-119997 Disulergine Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris Gh NCBI
Susscrofa domestica Gh NCBI
Leporidae Gh NCBI
Rattus norvegicus Gh NCBI
Macaca mulatta Gh NCBI
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