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  2. CNIH3 - cornichon family AMPA receptor auxiliary protein 3 Gene

CNIH3 - cornichon family AMPA receptor auxiliary protein 3 Gene

中文名称:cornichon 家族 AMPA 受体辅助蛋白 3

种属: Homo sapiens

同用名: CNIH-3

基因 ID: 149111 | 基因类型: protein coding

关于 CNIH3

This gene has 14 transcripts (splice variants), 194 orthologues and 4 paralogues. Biased expression in brain (RPKM 4.8), testis (RPKM 1.6) and 10 other tissues.

功能概要

预测启用通道调节器活动。参与调节 AMPA 受体活性。预测位于树突轴和突触后膜。预计是 AMPA 谷氨酸受体复合物的一部分。预测在树突和谷氨酸能突触中活跃。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable channel regulator activity. Involved in regulation of AMPA Receptor activity. Predicted to be located in dendritic shaft and postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in dendrite and glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2022]

CNIH3 基因产物(5)

mRNA Protein Name
NM_001322302.2 NP_001309231.1 protein cornichon homolog 3 isoform 2
NM_001322303.2 NP_001309232.1 protein cornichon homolog 3 isoform 3
NM_001322304.2 NP_001309233.1 protein cornichon homolog 3 isoform 4
NM_001322305.2 NP_001309234.1 protein cornichon homolog 3 isoform 5
NM_152495.2 NP_689708.1 protein cornichon homolog 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of AMPA receptor activity IDA
IDA: 通过直接分析推断
20805473 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CNIH3 蛋白结构

Cornichon

Cornichon: Cornichon protein (1 - 48)

Cornichon

Cornichon: Cornichon protein (59 - 152)

  • 0
  • 100
  • 160 a.a.
蛋白主名 其他名称

protein cornichon homolog 3

cornichon homolog 3

CNIH3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CNIH3 Q8TBE1 SORT1 Homo sapiens Q99523
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 SORT1 Homo sapiens Q99523
Y2H Array
32296183
Intra CNIH3 Q8TBE1 SORT1 Homo sapiens Q99523
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 NEMP1 Homo sapiens O14524-2
Y2H Array
32296183
Intra CNIH3 Q8TBE1 NEMP1 Homo sapiens O14524-2
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 LRRC25 Homo sapiens Q8N386
Y2H Array
32296183
Intra CNIH3 Q8TBE1 LRRC25 Homo sapiens Q8N386
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMEM80 Homo sapiens Q96HE8
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 TMEM80 Homo sapiens Q96HE8
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 TMEM80 Homo sapiens Q96HE8
Y2H Array
32296183
Intra CNIH3 Q8TBE1 STOM Homo sapiens P27105
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 STOM Homo sapiens P27105
Y2H Array
32296183
Intra CNIH3 Q8TBE1 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 ODF4 Homo sapiens Q2M2E3
Y2H Array
32296183
Intra CNIH3 Q8TBE1 ODF4 Homo sapiens Q2M2E3
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 CEACAM3 Homo sapiens P40198
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 CEACAM3 Homo sapiens P40198
Y2H Array
32296183
Intra CNIH3 Q8TBE1 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra CNIH3 Q8TBE1 LEUTX Homo sapiens A8MZ59
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 LEUTX Homo sapiens A8MZ59
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra CNIH3 Q8TBE1 SUSD3 Homo sapiens Q96L08
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 SUSD3 Homo sapiens Q96L08
Y2H Array
32296183
Intra CNIH3 Q8TBE1 SUSD3 Homo sapiens Q96L08
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 FAM210B Homo sapiens Q96KR6
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
Intra CNIH3 Q8TBE1 CLDN20 Homo sapiens P56880
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 CLDN20 Homo sapiens P56880
Y2H Array
32296183
Intra CNIH3 Q8TBE1 PLD3 Homo sapiens Q8IV08
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 PLD3 Homo sapiens Q8IV08
Y2H Array
32296183
Intra CNIH3 Q8TBE1 KCNN4 Homo sapiens O15554
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 KCNN4 Homo sapiens O15554
Y2H Array
32296183
Intra CNIH3 Q8TBE1 BIK Homo sapiens Q13323
Y2H Array
32296183
Intra CNIH3 Q8TBE1 BIK Homo sapiens Q13323
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 SMIM3 Homo sapiens Q9BZL3
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 SMIM3 Homo sapiens Q9BZL3
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 SMIM3 Homo sapiens Q9BZL3
Y2H Array
32296183
Intra CNIH3 Q8TBE1 VSIR Homo sapiens Q9H7M9
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 VSIR Homo sapiens Q9H7M9
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 VSIR Homo sapiens Q9H7M9
Y2H Array
32296183
Intra CNIH3 Q8TBE1 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
Intra CNIH3 Q8TBE1 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
Intra CNIH3 Q8TBE1 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
Intra CNIH3 Q8TBE1 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra CNIH3 Q8TBE1 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra CNIH3 Q8TBE1 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra CNIH3 Q8TBE1 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra CNIH3 Q8TBE1 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Splenic Artery Aneurysm

Aneurysm Of Splenic Artery

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CNIH3 VGNC VGNC:39401
Macaca mulatta CNIH3 VGNC VGNC:71359
Felis catus CNIH3 VGNC VGNC:107860
Rattus norvegicus CNIH3 RGD RGD:1582859
Mus musculus CNIH3 MGD MGI:1920228
Bos taurus CNIH3 VGNC VGNC:27503