2. Gene
  3. Lcat - lecithin cholesterol acyltransferase Gene

Lcat - lecithin cholesterol acyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: D8Wsu61e

基因 ID: 16816 | 基因类型: protein coding

关于 Lcat

功能概要

Enables phosphatidylcholine-sterol O-acyltransferase activity and platelet-activating factor acetyltransferase activity. Involved in regulation of high-density lipoprotein particle assembly. Acts upstream of or within Cholesterol metabolic process and lipoprotein biosynthetic process. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and integumental system. Used to study Norum disease. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Orthologous to human LCAT (lecithin-cholesterol Acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Lcat 基因产物(1)

mRNA Protein Name
NM_008490.2 NP_032516.2 phosphatidylcholine-sterol acyltransferase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphatidylcholine-sterol O-acyltransferase activity IDA
IDA: 通过直接分析推断
9300780 MGI
enables platelet-activating factor acetyltransferase activity IDA
IDA: 通过直接分析推断
10393212 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cholesterol metabolic process IDA
IDA: 通过直接分析推断
9300780 MGI
acts upstream of or within lipoprotein biosynthetic process IDA
IDA: 通过直接分析推断
16245952 MGI
involved in regulation of high-density lipoprotein particle assembly IDA
IDA: 通过直接分析推断
19065001 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
10549415 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphatidylcholine-sterol acyltransferase

1-alkyl-2-acetylglycerophosphocholine esterase

PAF acetylhydrolase

lecithin-cholesterol acyltransferase Lcat

phospholipid-cholesterol acyltransferase

platelet-activating factor acetylhydrolase

重组 Lcat 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77979 LCAT Protein, Mouse (HEK293, His) P16301 (F25-E438) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-146584 Cathepsin C-IN-5 Inhibitor 95.01% 否
HY-P5282 ApoA-I mimetic peptide Activator 98.10% 否
HY-RS07549 LCAT Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lcat NCBI NCBI:3931
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