2. Gene
  3. Epcam - epithelial cell adhesion molecule Gene

Epcam - epithelial cell adhesion molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EGP; Ly74; gp40; CD326; EGP-2; TROP1; Egp314; Ep-CAM; EpCAM1; Tacsd1; GA733-2; Tacstd1

基因 ID: 17075 | 基因类型: protein coding

关于 Epcam

功能概要

Predicted to enable cadherin binding activity involved in cell-cell adhesion. Acts upstream of or within ureteric bud development. Located in cell surface. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study congenital diarrhea 5 with tufting enteropathy. Human ortholog(s) of this gene implicated in congenital diarrhea 5 with tufting enteropathy and hereditary nonpolyposis colorectal Cancer type 8. Orthologous to human EPCAM (epithelial cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Epcam 基因产物(1)

mRNA Protein Name
NM_008532.2 NP_032558.2 epithelial cell adhesion molecule precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ureteric bud development IEP
IEP: 通过表达模式推断
16545622 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
17599412 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

epithelial cell adhesion molecule

Trop-1 protein

epithelial glycoprotein 314

lymphocyte antigen 74

mEGP314

panepithelial glycoprotein 314

protein 289A

tumor-associated calcium signal transducer 1

重组 Epcam 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70900 EpCAM/TROP1 Protein, Mouse (HEK293, Fc) Q99JW5 (Q24-T266) ≥95%
HY-P78704 EpCAM/TROP1 Protein, Mouse (HEK293, His) Q99JW5/AAH05618.1 (Q24-T266) ≥95%

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9954 Catumaxomab 98.56% 否
Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P99328 Tucotuzumab ≥95.0% Phase 2
HY-P99592 Solitomab Inhibitor 98.22% Phase 1
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15897 LDN-212854 Inhibitor 99.70% 否
HY-111183 Neocarzinostatin ≥99.0% 否
HY-RS04420 EPCAM Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epcam NCBI NCBI:4072
Macaca fascicularis Epcam NCBI NCBI:102123042
Rattus norvegicus Epcam NCBI NCBI:171577
Macaca mulatta Epcam NCBI NCBI:677680
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