2. Gene
  3. Nqo1 - NAD(P)H dehydrogenase, quinone 1 Gene

Nqo1 - NAD(P)H dehydrogenase, quinone 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Dtd; Ox1; Qr1; Dia4; Nmo1; Ox-1; Nmo-1; Nmor1

基因 ID: 18104 | 基因类型: protein coding

关于 Nqo1

功能概要

Enables NAD(P)H dehydrogenase (quinone) activity. Acts upstream of or within negative regulation of catalytic activity and response to oxidative stress. Predicted to be located in cytoplasm; dendrite; and neuronal cell body. Predicted to be active in cytosol. Is expressed in heart; main olfactory bulb; olfactory epithelium; and skin. Human ortholog(s) of this gene implicated in several diseases, including asthma; hematologic Cancer (multiple); lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nqo1 基因产物(1)

mRNA Protein Name
NM_008706.5 NP_032732.3 NAD(P)H dehydrogenase [quinone] 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NAD(P)H dehydrogenase (quinone) activity IDA
IDA: 通过直接分析推断
1914521 MGI
enables NADH:ubiquinone reductase (non-electrogenic) activity IDA
IDA: 通过直接分析推断
8999809 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
29934320 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytokine production IMP
IMP: 通过突变表型推断
29934320 MGI
involved in innate immune response IMP
IMP: 通过突变表型推断
29934320 MGI
acts upstream of or within negative regulation of catalytic activity IDA
IDA: 通过直接分析推断
10903442 MGI
involved in protein catabolic process IDA
IDA: 通过直接分析推断
29934320 MGI
involved in protein polyubiquitination IDA
IDA: 通过直接分析推断
29934320 MGI
involved in response to lipopolysaccharide IMP
IMP: 通过突变表型推断
29934320 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
15386390 MGI
involved in vitamin K metabolic process IDA
IDA: 通过直接分析推断
8999809 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
29934320 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
29934320 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NAD(P)H dehydrogenase [quinone] 1

DT-diaphorase

NAD(P)H dehydrogenase (quinone)

NAD(P)H menadione oxidoreductase 1, dioxin inducible

NAD(P)H:quinone oxidoreductase 1

azoreductase

diaphorase 4 (NADH/NADPH)

menadione reductase

phylloquinone reductase

quinone reductase 1

重组 Nqo1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71831 Azoreductase/NQO1 Protein, Mouse (P.pastoris, His) Q64669 (A2-K274) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-N0645 Dicoumarol Inhibitor 99.89% 否
Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-128895 KL1333 Modulator ≥98.0% Phase 2
HY-13543 Tretazicar 99.65% Phase 2
HY-149021 Tubulin polymerization-IN-28 / Phase 1
Pre-clinical Phase
生物活性分子 (37)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-110258 ML334 Activator 99.76% 否
HY-30267 4-Hydroxyphenyl acetate 99.98% 否
HY-120371 CPUY192018 Inhibitor 98.99% 否
HY-125027 Isobutyl-deoxynyboquinone 99.70% 否
HY-15673 KP372-1 99.75% 否
HY-103667 2-HBA Activator 99.09% 否
HY-100367 ES 936 97.50% 否
HY-114315 NQO1 substrate Substrate 98.02% 否
HY-N7335 Dehydroglyasperin C 99.12% 否
HY-108992 Deoxynyboquinone Inducer 99.21% 否
HY-110258B (R,S,R)-ML334 Control 98.57% 否
HY-122915 Zedoarondiol Inhibitor 98.99% 否
HY-121523 MIND4-17 Activator 99.93% 否
HY-N6802 Tigloylgomisin H Inducer / 否
HY-107736 AI-3 Activator / 否
HY-118588 Diminutol Inhibitor / 否
HY-123903 Tanshindiol B Activator / 否
HY-141439 TBE 31 Activator / 否
HY-146048 Antitumor agent-57 Inducer / 否
HY-146114 Antitumor agent-67 / 否
HY-146577 Keap1-Nrf2-IN-7 Inhibitor / 否
HY-146578 Keap1-Nrf2-IN-8 Inhibitor / 否
HY-147795 Nampt-IN-8 / 否
HY-148480 Nrf2 activator-6 Activator / 否
HY-149245 Keap1-Nrf2-IN-15 Inhibitor / 否
HY-150971 ICy-Q Inducer / 否
HY-163772 Fraxinellone analog 1 Activator / 否
HY-167694 Antiproliferative agent-62 / 否
HY-168526 Keap1-Nrf2-IN-24 Inhibitor / 否
HY-170301 Keap1-IN-1 Inhibitor / 否
HY-171035 PRL-295 Inhibitor / 否
HY-N10344 Glucoarabin / 否
HY-N14116 Garlic oil Inducer / 否
HY-N15190 Sesaminol / 否
HY-RS09523 NQO1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-147548 Keap1-Nrf2-IN-10 Inhibitor / 否
HY-162096 Keap1-Nrf2-IN-17 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nqo1 NCBI NCBI:1728
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