2. Gene
  3. Pgr - progesterone receptor Gene

Pgr - progesterone receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：孕激素受体

种属: Mus musculus

同用名: PR; PR-A; PR-B; NR3C3; 9930019P03Rik

基因 ID: 18667 | 基因类型: protein coding

关于 Pgr

Chromosome 9: 8,899,834-8,968,612 forward strand.GRCm39:CM001002.3

This gene has 4 transcripts (splice variants), 193 orthologues, 8 paralogues and is associated with 51 phenotypes. Biased expression in subcutaneous fat pad adult (RPKM 5.5), ovary adult (RPKM 4.9) and 6 other tissues.

功能概要

该基因编码类固醇受体超家族的一个成员。编码的蛋白质介导黄体酮的生理效应，黄体酮在与妊娠的建立和维持相关的生殖事件中起着核心作用。 [RefSeq 提供，2015 年 9 月]

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. [provided by RefSeq, Sep 2015]

Pgr 基因产物(1)

mRNA Protein Name
NM_008829.2 NP_032855.2 progesterone receptor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nuclear receptor activity IMP
IMP: 通过突变表型推断
14681235 MGI
enables nuclear steroid receptor activity IDA
IDA: 通过直接分析推断
16176985 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8978696 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within epithelial cell maturation IMP
IMP: 通过突变表型推断
14765981 MGI
acts upstream of or within glandular epithelial cell maturation IMP
IMP: 通过突变表型推断
14765981 MGI
acts upstream of or within lung alveolus development IMP
IMP: 通过突变表型推断
24190884 MGI
acts upstream of or within mammary gland development IMP
IMP: 通过突变表型推断
12897242 MGI
acts upstream of or within ovulation from ovarian follicle IMP
IMP: 通过突变表型推断
12897242 MGI
acts upstream of or within paracrine signaling IMP
IMP: 通过突变表型推断
24190884 MGI
acts upstream of or within progesterone receptor signaling pathway IDA
IDA: 通过直接分析推断
16176985 MGI
acts upstream of or within regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
14681235 MGI
acts upstream of or within regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
12897242 MGI
acts upstream of or within tertiary branching involved in mammary gland duct morphogenesis IMP
IMP: 通过突变表型推断
10733525 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Pgr 蛋白结构

Prog_receptor

Prog_receptor: pfam02161 (0 - 556)

NR_DBD_GR_PR

NR_DBD_GR_PR: cd07172 (555 - 632)

NR_LBD_PR

NR_LBD_PR: cd07074 (678 - 925)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 926 a.a.
蛋白主名 其他名称

progesterone receptor

nuclear receptor subfamily 3 group C member 3

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10396 PGR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10397 Pgr Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10398 Pgr Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-164997 15-keto Prostaglandin F1α / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pgr NCBI NCBI:5241
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