2. Gene
  3. Ppp2ca - protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform Gene

Ppp2ca - protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PP2A

基因 ID: 19052 | 基因类型: protein coding

关于 Ppp2ca

功能概要

Enables GABA Receptor binding activity and protein C-terminus binding activity. Acts upstream of or within mesoderm development. Located in chromosome, centromeric region; cytosol; and plasma membrane. Part of protein Phosphatase type 2A complex. Is active in synapse. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PPP2CA (protein Phosphatase 2 catalytic subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2ca 基因产物(1)

mRNA Protein Name
NM_019411.4 NP_062284.1 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GABA receptor binding IDA
IDA: 通过直接分析推断
16754670 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9920888 MGI
enables protein serine/threonine phosphatase activity IMP
IMP: 通过突变表型推断
26974206 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell homeostasis IMP
IMP: 通过突变表型推断
26974206 MGI
acts upstream of or within mesoderm development IMP
IMP: 通过突变表型推断
9770493 MGI
involved in negative regulation of glycolytic process through fructose-6-phosphate IMP
IMP: 通过突变表型推断
32192773 MGI
involved in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
26974206 MGI
involved in positive regulation of NLRP3 inflammasome complex assembly IMP
IMP: 通过突变表型推断
28465465 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, centromeric region IDA
IDA: 通过直接分析推断
18084284 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
9882488 MGI
located in cytosol IDA
IDA: 通过直接分析推断
12885400 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10781942 MGI
part of protein phosphatase type 2A complex IDA
IDA: 通过直接分析推断
16717086 MGI
is active in synapse IDA
IDA: 通过直接分析推断
16420440 MGI
is active in synapse IEP
IEP: 通过表达模式推断
16420440 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

PP2A-alpha

Ppp2ca 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Ppp2ca P63330 Ppp2r1a Mus musculus Q76MZ3
Anti Bait CoIP
19818709
种属内
Ppp2ca P63330 Igbp1 Mus musculus Q61249
Anti Bait CoIP
19818709
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11007 PPP2CA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ppp2ca NCBI NCBI:5515
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