1. Gene
  2. Igbp1 - immunoglobulin (CD79A) binding protein 1 Gene

Igbp1 - immunoglobulin (CD79A) binding protein 1 Gene

种属: Mus musculus

同用名: p52; Pc52; Tap42

基因 ID: 18518 | 基因类型: protein coding

关于 Igbp1

功能概要

Enables mitogen-activated protein kinase kinase binding activity and protein domain specific binding activity. Involved in negative regulation of protein dephosphorylation; positive regulation of dephosphorylation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of apoptotic signaling pathway. Located in cytoplasm and microtubule. Is expressed in bladder; female associated reproductive structure; ovary; ureter; and urethra of female. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to human IGBP1 (immunoglobulin binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Igbp1 基因产物(1)

mRNA Protein Name
NM_008784.3 NP_032810.4 immunoglobulin-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
11806752 MGI
enables mitogen-activated protein kinase kinase binding IPI
IPI: 通过物理相互作用推断
17438131 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12963337 MGI
enables protein domain specific binding IDA
IDA: 通过直接分析推断
11806752 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: 通过突变表型推断
15499020 MGI
involved in positive regulation of dephosphorylation IMP
IMP: 通过突变表型推断
15499020 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15499020 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11806752 MGI
located in microtubule IGI
IGI: 通过遗传相互作用推断
11806752 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

immunoglobulin-binding protein 1

CD79a-binding protein 1

alpha 4

alpha4 phosphoprotein

lymphocyte signal transduction molecule alpha 4

phosphoprotein, component, 52 kDa

protein phosphatase 2/4/6 regulatory subunit

Igbp1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Igbp1 Q61249 Ppp2ca Mus musculus P63330
Anti Bait CoIP
19818709
种属间
Igbp1 Q61249 PPP2CA Homo sapiens P67775
CoIP
12963337
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Igbp1 NCBI NCBI:3476