Igbp1 - immunoglobulin (CD79A) binding protein 1 Gene

种属: Mus musculus

同用名: p52; Pc52; Tap42

关于 Igbp1

功能概要

Enables mitogen-activated protein kinase kinase binding activity and protein domain specific binding activity. Involved in negative regulation of protein dephosphorylation; positive regulation of dephosphorylation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of apoptotic signaling pathway. Located in cytoplasm and microtubule. Is expressed in bladder; female associated reproductive structure; ovary; ureter; and urethra of female. Human ortholog(s) of this gene implicated in corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome. Orthologous to human IGBP1 (immunoglobulin binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]