AGO3 - argonaute RISC catalytic component 3 Gene

中文名称：argonaute RISC 催化组分 3

种属: Homo sapiens

同用名: EIF2C3

关于 AGO3

功能概要

该基因编码在 RNA 干扰中发挥作用的 Argonaute 蛋白家族成员。编码的蛋白质是高度碱性的，包含一个 PAZ 结构域和一个 PIWI 结构域，可能在短干扰 RNA 介导的基因沉默中发挥作用。该基因位于 1 号染色体上，由一系列密切相关的家族成员组成，包括 argonaute 4 和真核翻译起始因子 2C，1。已为该基因鉴定了编码不同亚型的两个转录变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]