SCAMP5 - secretory carrier membrane protein 5 Gene

中文名称：分泌性载体膜蛋白 5

种属: Homo sapiens

基因 ID: 192683 | 基因类型: protein coding

关于 SCAMP5

Cytogenetic location: 15q24.2 Genomic coordinates (GRCh38): 15:74,995,563-75,021,495 (from NCBI)

This gene has 18 transcripts (splice variants), 278 orthologues and 4 paralogues. Biased expression in brain (RPKM 81.6), duodenum (RPKM 16.5) and 6 other tissues.

功能概要

参与细胞因子产生的正向调节；调节囊泡介导的运输；和对内质网应激的反应。位于高尔基体；质膜;和回收内体膜。是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Involved in positive regulation of cytokine production; regulation of vesicle-mediated transport; and response to endoplasmic reticulum stress. Located in Golgi apparatus; plasma membrane; and recycling endosome membrane. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SCAMP5 基因产物(3)

mRNA	Protein	Name
NM_001178111.2	NP_001171582.1	secretory carrier-associated membrane protein 5
NM_001178112.2	NP_001171583.1	secretory carrier-associated membrane protein 5
NM_138967.4	NP_620417.1	secretory carrier-associated membrane protein 5

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	15840657	GOA
enables protein-containing complex binding	IDA IDA: 通过直接分析推断	19234194	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in negative regulation of endocytosis	IDA IDA: 通过直接分析推断	19240033	GOA
involved in positive regulation of calcium ion-dependent exocytosis	IDA IDA: 通过直接分析推断	19234194	GOA
involved in positive regulation of cytokine production	IDA IDA: 通过直接分析推断	19234194	GOA
involved in response to endoplasmic reticulum stress	IDA IDA: 通过直接分析推断	19240033	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in Golgi membrane	IDA IDA: 通过直接分析推断	19234194	GOA
located in membrane	IDA IDA: 通过直接分析推断	19234194	GOA
located in plasma membrane	IDA IDA: 通过直接分析推断	19234194	GOA
located in recycling endosome membrane	IDA IDA: 通过直接分析推断	15840657	GOA
located in trans-Golgi network membrane	IDA IDA: 通过直接分析推断	15840657	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SCAMP5 蛋白结构

SCAMP

0
100
200
235 a.a.

蛋白主名

其他名称

secretory carrier-associated membrane protein 5

hSCAMP5

SCAMP5 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	SCAMP5	Q8TAC9	SGPL1	Homo sapiens	O95470	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	SGPL1	Homo sapiens	O95470	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	TLCD4	Homo sapiens	Q96MV1	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	TLCD4	Homo sapiens	Q96MV1	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	TLCD4	Homo sapiens	Q96MV1	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	PITPNC1	Homo sapiens	Q9UKF7-2	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	MUC1	Homo sapiens	P15941-11	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	MUC1	Homo sapiens	P15941-11	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	PIGP	Homo sapiens	P57054	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	PIGP	Homo sapiens	P57054	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	SHISAL1	Homo sapiens	Q3SXP7	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	SHISAL1	Homo sapiens	Q3SXP7	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	HSD17B13	Homo sapiens	Q7Z5P4	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	SLC10A6	Homo sapiens	Q3KNW5	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	CERS4	Homo sapiens	Q9HA82	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	CERS4	Homo sapiens	Q9HA82	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	CERS4	Homo sapiens	Q9HA82	Y2H Array	32296183
种属间	SCAMP5	Q8TAC9	Syt1	Mus musculus	P46096	Pull Down	19234194
种属间	SCAMP5	Q8TAC9	Syt1	Mus musculus	P46096	Anti Bait CoIP	19234194
种属间	SCAMP5	Q8TAC9	Syt2	Mus musculus	P46097	Pull Down	19234194
种属间	SCAMP5	Q8TAC9	Syt2	Mus musculus	P46097	Anti Bait CoIP	19234194
种属内	SCAMP5	Q8TAC9	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	TIMMDC1	Homo sapiens	Q9NPL8	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	TIMMDC1	Homo sapiens	Q9NPL8	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	SH3GL1	Homo sapiens	Q99961	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	FATE1	Homo sapiens	Q969F0	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	FATE1	Homo sapiens	Q969F0	Y2H Prey Pooling	32296183
种属内	SCAMP5	Q8TAC9	FATE1	Homo sapiens	Q969F0	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	TMEM14B	Homo sapiens	Q9NUH8	Y2H Array	32296183
种属内	SCAMP5	Q8TAC9	TMEM14B	Homo sapiens	Q9NUH8	Validated Y2H	32296183
种属内	SCAMP5	Q8TAC9	TMEM14B	Homo sapiens	Q9NUH8	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Chromosome 15q24 Deletion Syndrome

15q24 Microdeletion Syndrome	Del(15)(Q24)
Monosomy 15q24	15q24 Microdeletion
15q24 Deletion	Interstitial Deletion Of Chromosome 15q24

Atrial Septal Defect 1

ASD1	Atrial Heart Septal Defect 1
Asd

Autosomal Recessive Intellectual Developmental Disorder

Mental Retardation, Autosomal Recessive	Autosomal Recessive Mental Retardation
Autosomal Recessive Non-Syndromic Mental Retardation	Autosomal Recessive Non-Syndromic Intellectual Disability

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12482	SCAMP5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	SCAMP5	RGD	RGD:68356
Mus musculus	SCAMP5	MGD	MGI:1928948
Bos taurus	SCAMP5	VGNC	VGNC:34319
Felis catus	SCAMP5	VGNC	VGNC:64897
Canis familiaris	SCAMP5	VGNC	VGNC:45893
Macaca mulatta	SCAMP5	VGNC	VGNC:77136

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SCAMP5 - secretory carrier membrane protein 5 Gene

关于 SCAMP5

功能概要

SCAMP5 基因产物(3)

SCAMP5 蛋白结构

SCAMP5 蛋白互作信息

关联疾病

直系同源

热门区域

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SCAMP5 - secretory carrier membrane protein 5 Gene

关于 SCAMP5

功能概要

SCAMP5 基因产物(3)

SCAMP5 蛋白结构

SCAMP5 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z