2. Gene
  3. Khdrbs1 - KH domain containing, RNA binding, signal transduction associated 1 Gene

Khdrbs1 - KH domain containing, RNA binding, signal transduction associated 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p62; p68; Sam68

基因 ID: 20218 | 基因类型: protein coding

关于 Khdrbs1

功能概要

Enables several functions, including identical protein binding activity; protein tyrosine kinase binding activity; and signaling adaptor activity. Involved in cell surface receptor signaling pathway and regulation of mRNA splicing, via spliceosome. Acts upstream of or within negative regulation of transcription by RNA polymerase II and regulation of RNA export from nucleus. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; future brain; and gonad. Orthologous to human KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Khdrbs1 基因产物(1)

mRNA Protein Name
NM_011317.4 NP_035447.3 KH domain-containing, RNA-binding, signal transduction-associated protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
9315629 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
10077576 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10077576 MGI
enables protein tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
7799925 MGI
enables signaling adaptor activity IDA
IDA: 通过直接分析推断
7799925 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
7799925 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12496368 MGI
acts upstream of or within regulation of RNA export from nucleus IDA
IDA: 通过直接分析推断
12496368 MGI
involved in regulation of mRNA splicing, via spliceosome IDA
IDA: 通过直接分析推断
22196734 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12496368 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

KH domain-containing, RNA-binding, signal transduction-associated protein 1

GAP-associated tyrosine phosphoprotein p62

p21 Ras GTPase-activating protein-associated p62

src associated in mitosis, 68 kDa

src-associated in mitosis 68 kDa protein

Khdrbs1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Khdrbs1 Q60749 Crebbp Mus musculus P45481
Y2H
12496368
种属内
Khdrbs1 Q60749 Crebbp Mus musculus P45481
CoIP
12496368
种属内
Khdrbs1 Q60749 Fyn Mus musculus P39688
Pull Down
10077576
种属内
Khdrbs1 Q60749 Khdrbs1 Mus musculus Q60749
Anti Tag CoIP
10077576
种属间
Khdrbs1 Q60749 Plcg1 Rattus norvegicus P10686
Pull Down
10077576
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07237 KHDRBS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Khdrbs1 NCBI NCBI:10657
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