Scd1 - stearoyl-Coenzyme A desaturase 1 Gene

中文名称：硬脂酰辅酶 A 去饱和酶 1

种属: Mus musculus

同用名: ab; Scd; Scd-1

关于 Scd1

功能概要

该基因编码的蛋白可启动金属离子结合活性；棕榈酰辅酶 A 9-去饱和酶活性；和硬脂酰辅酶 A 9-去饱和酶活性。参与多个过程，包括胆固醇酯化；冷诱导产热的正调节；和跗骨腺发育。作用于多个过程的上游或内部，包括棕色脂肪细胞分化；单不饱和脂肪酸生物合成过程；和白色脂肪细胞分化。是内质网膜的组成部分。以多种结构表达，包括脂肪组织；中枢神经系统;颅骨;外皮系统；和肝脏。该基因的人类直向同源基因与常染色体显性非综合征性耳聋 79 相关。与包括 SCD（硬脂酰辅酶 A 去饱和酶）在内的几种人类基因直向同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables metal ion binding activity; palmitoyl-CoA 9-desaturase activity; and stearoyl-CoA 9-desaturase activity. Involved in several processes, including Cholesterol esterification; positive regulation of cold-induced thermogenesis; and tarsal gland development. Acts upstream of or within several processes, including brown fat cell differentiation; monounsaturated fatty acid biosynthetic process; and white fat cell differentiation. Is integral component of endoplasmic reticulum membrane. Is expressed in several structures, including adipose tissue; central nervous system; cranium; integumental system; and liver. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Orthologous to several human genes including SCD (stearoyl-CoA desaturase). [provided by Alliance of Genome Resources, Apr 2022]