2. Gene
  3. Ccl5 - chemokine (C-C motif) ligand 5 Gene

Ccl5 - chemokine (C-C motif) ligand 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SISd; Scya5; RANTES; TCP228; MuRantes

基因 ID: 20304 | 基因类型: protein coding

关于 Ccl5

功能概要

Enables CCR1 Chemokine Receptor binding activity. Involved in negative regulation of macrophage apoptotic process and positive regulation of monocyte chemotaxis. Acts upstream of or within inflammatory response; positive regulation of epithelial cell proliferation; and response to tumor necrosis factor. Located in cytoplasm and extracellular space. Is expressed in several structures, including central nervous system; gonad; hemolymphoid system; late tubule; and retina. Human ortholog(s) of this gene implicated in several diseases, including hepatitis B; hepatitis C; liver disease (multiple); pulmonary tuberculosis; and severe acute respiratory syndrome. Orthologous to human CCL5 (C-C motif chemokine ligand 5). [provided by Alliance of Genome Resources, Apr 2022]

Ccl5 基因产物(1)

mRNA Protein Name
NM_013653.3 NP_038681.2 C-C motif chemokine 5 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CCR1 chemokine receptor binding IDA
IDA: 通过直接分析推断
15557190 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of epithelial cell proliferation IMP
IMP: 通过突变表型推断
23696660 MGI
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
23696660 MGI
involved in negative regulation of macrophage apoptotic process IMP
IMP: 通过突变表型推断
16208318 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
23696660 MGI
involved in positive regulation of monocyte chemotaxis IDA
IDA: 通过直接分析推断
19779041 MGI
acts upstream of or within response to cytokine IDA
IDA: 通过直接分析推断
1375672 MGI
acts upstream of or within response to tumor necrosis factor IDA
IDA: 通过直接分析推断
1375672 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
1375672 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
21148126 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 5

SIS-delta

T-cell-specific protein RANTES

small-inducible cytokine A5

重组 Ccl5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71890 RANTES/CCL5 Protein, Mouse P30882 (S24-S91) ≥95%
HY-P78249 RANTES/CCL5 Protein, Mouse (HEK293, Fc) P30882 (S24-S91) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-152293 EVT801 Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15589 GW9508 99.33% 否
HY-152956 STING agonist-23 Agonist 99.16% 否
HY-147660 IMMH001 Agonist 98.10% 否
HY-122891 SB02024 99.7% 否
HY-152959 STING agonist-26 Agonist 99.56% 否
HY-P1949A Cyclic MKEY TFA 95.02% 否
HY-152957 STING agonist-24 Agonist / 否
HY-152958 STING agonist-25 Agonist / 否
HY-152961 STING agonist-28 Agonist / 否
HY-N12110 SMU-CX1 Inhibitor / 否
HY-P1949 Cyclic MKEY / 否
HY-P5836 Citrullinated LL-37 1cit Inhibitor / 否
HY-P5837 Citrullinated LL-37 2cit Inhibitor / 否
HY-P5843 Citrullinated LL-37 4cit Inhibitor / 否
HY-RS02105 CCL5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-111198 YM-355179 fumarate / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl5 NCBI NCBI:6352
Rattus norvegicus Ccl5 NCBI NCBI:81780
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