2. Gene
  3. Ccl5 - C-C motif chemokine ligand 5 Gene

Ccl5 - C-C motif chemokine ligand 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Scya5; Rantes

基因 ID: 81780 | 基因类型: protein coding

关于 Ccl5

功能概要

Enables chemokine activity and heparin binding activity. Involved in several processes, including cellular response to organonitrogen compound; lymphocyte migration; and positive regulation of leukocyte chemotaxis. Located in extracellular space. Used to study Chagas disease; bronchiolitis obliterans; kidney disease; non-alcoholic fatty liver disease; and orchitis. Biomarker of several diseases, including alcoholic hepatitis; artery disease (multiple); cardiac arrest; lung disease (multiple); and uveitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including hepatitis B; hepatitis C; liver disease (multiple); pulmonary tuberculosis; and severe acute respiratory syndrome. Orthologous to human CCL5 (C-C motif chemokine ligand 5). [provided by Alliance of Genome Resources, Apr 2022]

Ccl5 基因产物(1)

mRNA Protein Name
NM_031116.3 NP_112378.2 C-C motif chemokine 5 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
11069838 RGD
enables heparin binding IDA
IDA: 通过直接分析推断
21052646 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T-helper 1 cell diapedesis IDA
IDA: 通过直接分析推断
10477596 RGD
involved in cellular response to alkyl hydroperoxide IEP
IEP: 通过表达模式推断
18478184 RGD
involved in cellular response to amino acid stimulus IEP
IEP: 通过表达模式推断
20560880 RGD
involved in cellular response to cytokine stimulus IEP
IEP: 通过表达模式推断
19111021 RGD
involved in cellular response to ethanol IEP
IEP: 通过表达模式推断
19828633 RGD
involved in cellular response to high density lipoprotein particle stimulus IEP
IEP: 通过表达模式推断
20623482 RGD
involved in cellular response to lipid IEP
IEP: 通过表达模式推断
20638371 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
20578038 RGD
involved in cellular response to morphine IEP
IEP: 通过表达模式推断
20578038 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
20429874 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
20663893 RGD
involved in cellular response to vitamin K IEP
IEP: 通过表达模式推断
19291322 RGD
involved in chronic inflammatory response IEP
IEP: 通过表达模式推断
17164972 RGD
involved in dibenzo-p-dioxin metabolic process IEP
IEP: 通过表达模式推断
20059583 RGD
involved in lymphocyte chemotaxis IDA
IDA: 通过直接分析推断
11069838 RGD
involved in positive regulation of T cell chemotaxis IDA
IDA: 通过直接分析推断
10477596 RGD
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
18392345 RGD
involved in positive regulation of fever generation IDA
IDA: 通过直接分析推断
15066130 RGD
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
19497618 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
19559698 RGD
involved in positive regulation of mast cell chemotaxis IDA
IDA: 通过直接分析推断
18052723 RGD
involved in positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
19559698 RGD
involved in positive regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
9920817 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
10477596 RGD
involved in pseudopodium assembly IDA
IDA: 通过直接分析推断
10477596 RGD
involved in regulation of programmed cell death IMP
IMP: 通过突变表型推断
19497618 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
18464247 RGD
involved in response to alcohol IEP
IEP: 通过表达模式推断
11388697 RGD
involved in response to bacterium IEP
IEP: 通过表达模式推断
18390738 RGD
involved in response to cholesterol IEP
IEP: 通过表达模式推断
20435353 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
16251240 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
20435353 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
18476425 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
12435855 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19104678 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19194968 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18375833 RGD
involved in response to salt stress IEP
IEP: 通过表达模式推断
20232302 RGD
involved in response to type II interferon IDA
IDA: 通过直接分析推断
10477596 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16987901 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
18208670 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-C motif chemokine 5

SIS-delta

T-cell-specific protein RANTES

chemokine (C-C motif) ligand 5

regulated upon activation normal T-cell expressed and secreted

small-inducible cytokine A5

重组 Ccl5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7761 RANTES/CCL5 Protein, Rat (His) P50231 (S25-S92) ≥95%
HY-P74602 RANTES/CCL5 Protein, Rat (P.pastoris, His) P50231 (S25-S92) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-152293 EVT801 Inhibitor / Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990638 NI-0701 99.74% Phase 1
Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15589 GW9508 99.33% 否
HY-152956 STING agonist-23 Agonist 99.16% 否
HY-147660 IMMH001 Agonist 98.10% 否
HY-122891 SB02024 99.7% 否
HY-152959 STING agonist-26 Agonist 99.56% 否
HY-P1949A Cyclic MKEY TFA 95.02% 否
HY-111198 YM-355179 fumarate / 否
HY-152957 STING agonist-24 Agonist / 否
HY-152958 STING agonist-25 Agonist / 否
HY-152961 STING agonist-28 Agonist / 否
HY-N12110 SMU-CX1 Inhibitor / 否
HY-P1949 Cyclic MKEY / 否
HY-P5836 Citrullinated LL-37 1cit Inhibitor / 否
HY-P5837 Citrullinated LL-37 2cit Inhibitor / 否
HY-P5838 Citrullinated LL-37 5cit Inhibitor / 否
HY-P5843 Citrullinated LL-37 4cit Inhibitor / 否
HY-RS02105 CCL5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990677 VLST-002 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccl5 NCBI NCBI:6352
Mus musculus Ccl5 NCBI NCBI:20304
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