2. Gene
  3. Cx3cl1 - chemokine (C-X3-C motif) ligand 1 Gene

Cx3cl1 - chemokine (C-X3-C motif) ligand 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FK; CX3C; Cxc3; Scyd1; ABCD-3; D8Bwg0439e

基因 ID: 20312 | 基因类型: protein coding

关于 Cx3cl1

功能概要

Enables CX3C Chemokine Receptor binding activity and chemokine activity. Acts upstream of or within several processes, including angiogenesis involved in wound healing; leukocyte chemotaxis; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Located in several cellular components, including cell surface; neuron projection; and neuronal cell body. Is expressed in several structures, including brain; genitourinary system; gut; nose; and respiratory system. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Cx3cl1 基因产物(1)

mRNA Protein Name
NM_009142.3 NP_033168.2 fractalkine precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables CX3C chemokine receptor binding IDA
IDA: 通过直接分析推断
18971423 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within angiogenesis involved in wound healing IMP
IMP: 通过突变表型推断
18097059 MGI
acts upstream of or within cytokine-mediated signaling pathway IMP
IMP: 通过突变表型推断
18971423 MGI
acts upstream of extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
18322241 MGI
acts upstream of or within lymphocyte chemotaxis IDA
IDA: 通过直接分析推断
9177350 MGI
acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
18322241 MGI
acts upstream of or within neutrophil chemotaxis IDA
IDA: 通过直接分析推断
9177350 MGI
acts upstream of or within positive regulation of transforming growth factor beta1 production IMP
IMP: 通过突变表型推断
18097059 MGI
acts upstream of or within wound healing IMP
IMP: 通过突变表型推断
18097059 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell body IDA
IDA: 通过直接分析推断
12815711 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
12815711 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
12815711 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
28612258 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fractalkine

C-X3-C motif chemokine 1

CX3C membrane-anchored chemokine

neurotactin

small inducible cytokine subfamily D, 1

small-inducible cytokine D1

重组 Cx3cl1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72686 Fractalkine/CX3CL1 Protein, Mouse (HEK293, His) O35188 (Q25-R337) ≥95%
HY-P78113 Fractalkine/CX3CL1 Protein, Mouse (Biotinylated, HEK293, His-Avi) O35188 (Q25-T336) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03378 CX3CL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99404 Quetmolimab Inhibitor 95.00% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cx3cl1 NCBI NCBI:6376
Canis familiaris Cx3cl1 NCBI NCBI:487265
Macaca fascicularis Cx3cl1 NCBI NCBI:102117496
Rattus norvegicus Cx3cl1 NCBI NCBI:89808
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