2. Gene
  3. Cx3cl1 - C-X3-C motif chemokine ligand 1 Gene

Cx3cl1 - C-X3-C motif chemokine ligand 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cx3c; Scyd1

基因 ID: 89808 | 基因类型: protein coding

关于 Cx3cl1

功能概要

Enables chemokine activity. Involved in several processes, including positive regulation of cell population proliferation; regulation of gene expression; and regulation of signal transduction. Located in several cellular components, including neuron projection; neuronal cell body; and perinuclear region of cytoplasm. Used to study acute pancreatitis; ischemia; and status epilepticus. Biomarker of several diseases, including borna disease; brain disease (multiple); liver disease (multiple); lung disease (multiple); and pulmonary hypertension. Human ortholog(s) of this gene implicated in Cor pulmonale and common cold. Orthologous to human CX3CL1 (C-X3-C motif chemokine ligand 1). [provided by Alliance of Genome Resources, Apr 2022]

Cx3cl1 基因产物(1)

mRNA Protein Name
NM_134455.2 NP_604450.2 fractalkine precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chemokine activity IDA
IDA: 通过直接分析推断
9724801 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
12729461 RGD
involved in autocrine signaling IGI
IGI: 通过遗传相互作用推断
12729461 RGD
involved in cell-cell adhesion IDA
IDA: 通过直接分析推断
12729461 RGD
involved in cellular response to tumor necrosis factor IDA
IDA: 通过直接分析推断
12729461 RGD
involved in chemokine-mediated signaling pathway IGI
IGI: 通过遗传相互作用推断
12729461 RGD
involved in chemotaxis IDA
IDA: 通过直接分析推断
9724801 RGD
involved in chemotaxis IGI
IGI: 通过遗传相互作用推断
16019082 RGD
involved in inhibitory postsynaptic potential IMP
IMP: 通过突变表型推断
19748551 RGD
involved in microglial cell activation IDA
IDA: 通过直接分析推断
11870871 RGD
involved in negative regulation of glutamate receptor signaling pathway IDA
IDA: 通过直接分析推断
16019082 RGD
involved in negative regulation of interleukin-1 alpha production IDA
IDA: 通过直接分析推断
19627440 RGD
involved in negative regulation of vasoconstriction IDA
IDA: 通过直接分析推断
19201996 RGD
involved in neuron cellular homeostasis IDA
IDA: 通过直接分析推断
16019082 RGD
involved in positive regulation of canonical NF-kappaB signal transduction IGI
IGI: 通过遗传相互作用推断
12729461 RGD
involved in positive regulation of cell adhesion IDA
IDA: 通过直接分析推断
17114429 RGD
involved in positive regulation of cell migration IDA
IDA: 通过直接分析推断
17114429 RGD
involved in positive regulation of macrophage chemotaxis IMP
IMP: 通过突变表型推断
19282612 RGD
involved in positive regulation of neuroblast proliferation IDA
IDA: 通过直接分析推断
20018408 RGD
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
23825416 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
12729461 RGD
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
12729461 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12729461 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
18630689 RGD
involved in response to ischemia IGI
IGI: 通过遗传相互作用推断
12059974 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
11870871 RGD
located in extracellular region IDA
IDA: 通过直接分析推断
16019082 RGD
located in membrane IDA
IDA: 通过直接分析推断
16019082 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
15341587 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12059974 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11870871 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fractalkine

C-X3-C motif chemokine 1

CX3C membrane-anchored chemokine

chemokine (C-X3-C motif) ligand 1

neurotactin

small inducible cytokine subfamily D, 1

small-inducible cytokine D1

重组 Cx3cl1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P79193 Fractalkine/CX3CL1 Protein, Rat O55145 (L22-G100) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03378 CX3CL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99404 Quetmolimab Inhibitor 95.00% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cx3cl1 NCBI NCBI:6376
Canis familiaris Cx3cl1 NCBI NCBI:487265
Macaca fascicularis Cx3cl1 NCBI NCBI:102117496
Mus musculus Cx3cl1 NCBI NCBI:20312
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