1. Gene
  2. Mchr1 - melanin-concentrating hormone receptor 1 Gene

Mchr1 - melanin-concentrating hormone receptor 1 Gene

中文名称:黑色素浓缩激素受体 1

种属: Mus musculus

同用名: Gpr24; Mch1r

基因 ID: 207911 | 基因类型: protein coding

关于 Mchr1

Chromosome 15: 81,119,700-81,123,165 forward strand.GRCm39:CM001008.3

This gene has 1 transcript (splice variant), 241 orthologues, 55 paralogues and is associated with 35 phenotypes. Broad expression in cortex adult (RPKM 5.3), frontal lobe adult (RPKM 4.6) and 19 other tissues.

功能概要

该基因编码的蛋白可启动信号受体结合活性。预计参与多个过程,包括神经肽信号通路;正调节钙离子运输;和细胞溶质钙离子浓度的正调节。预测作用于 G 蛋白偶联受体信号通路的上游或内部。位于纤毛膜和非运动纤毛中。在脑和肺中表达。该基因的人类直系同源物与病态肥胖有关。与人类 MCHR1(黑色素浓缩激素受体 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables signaling receptor binding activity. Predicted to be involved in several processes, including neuropeptide signaling pathway; positive regulation of calcium ion transport; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in ciliary membrane and non-motile cilium. Is expressed in brain and lung. Human ortholog(s) of this gene implicated in morbid obesity. Orthologous to human MCHR1 (melanin concentrating hormone receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mchr1 基因产物(1)

mRNA Protein Name
NM_145132.2 NP_660114.1 melanin-concentrating hormone receptor 1

Mchr1 蛋白结构

7tmA_MCHR1

7tmA_MCHR1: cd15338 (40 - 321)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (41 - 67)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (77 - 103)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (115 - 145)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (157 - 177)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (204 - 233)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (248 - 278)

7tmA_MCHR1

7tmA_MCHR1: cd15338 (289 - 314)

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  • 353 a.a.
蛋白主名 其他名称

melanin-concentrating hormone receptor 1

G protein coupled receptor 24

Gpr24-9 protein coupled receptor

MCH receptor 1

MCHR

SLC-1

somatostatin receptor-like protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mchr1 NCBI NCBI:2847