2. Gene
  3. Sumo1 - small ubiquitin-like modifier 1 Gene

Sumo1 - small ubiquitin-like modifier 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: GMP1; PIC1; SMT3; Ubl1; SMTP3; Smt3C; SMT3H3; SUMO-1; SENTRIN

基因 ID: 22218 | 基因类型: protein coding

关于 Sumo1

功能概要

Predicted to enable Enzyme binding activity; Potassium Channel regulator activity; and protein tag. Involved in several processes, including positive regulation of ATPase-coupled calcium transmembrane transporter activity; regulation of cardiac muscle cell contraction; and regulation of protein stability. Acts upstream of or within several processes, including PML body organization; protein localization to nuclear pore; and protein sumoylation. Located in XY body and nuclear body. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and heart. Human ortholog(s) of this gene implicated in orofacial cleft 10. Orthologous to human SUMO1 (small ubiquitin like modifier 1). [provided by Alliance of Genome Resources, Apr 2022]

Sumo1 基因产物(1)

mRNA Protein Name
NM_009460.2 NP_033486.1 small ubiquitin-related modifier 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15767674 MGI
enables transcription factor binding IMP
IMP: 通过突变表型推断
15023536 MGI
enables transcription factor binding IPI
IPI: 通过物理相互作用推断
15767674 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within PML body organization IMP
IMP: 通过突变表型推断
19033381 MGI
involved in positive regulation of ATPase-coupled calcium transmembrane transporter activity IMP
IMP: 通过突变表型推断
21900893 MGI
acts upstream of or within protein localization to nuclear pore IMP
IMP: 通过突变表型推断
19033381 MGI
acts upstream of or within protein sumoylation IDA
IDA: 通过直接分析推断
15767674 MGI
acts upstream of or within protein sumoylation IMP
IMP: 通过突变表型推断
19033381 MGI
involved in protein sumoylation IMP
IMP: 通过突变表型推断
15023536 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15767674 MGI
involved in regulation of calcium ion transmembrane transport IMP
IMP: 通过突变表型推断
21900893 MGI
involved in regulation of cardiac muscle cell contraction IMP
IMP: 通过突变表型推断
21900893 MGI
involved in regulation of protein stability IMP
IMP: 通过突变表型推断
21900893 MGI
involved in roof of mouth development IMP
IMP: 通过突变表型推断
16990542 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in XY body IDA
IDA: 通过直接分析推断
25634095 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
31749687 MGI
located in nuclear body IDA
IDA: 通过直接分析推断
18681895 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15767674 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
31749687 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
31749687 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

small ubiquitin-related modifier 1

SMT3 homolog 3

SMT3 suppressor of mif two 3 homolog 1

SUMO-1 related peptidase

ubiquitin-homology domain protein PIC1

ubiquitin-like 1

ubiquitin-like protein SMT3C

Sumo1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Sumo1 P63166 Nr2c1 Mus musculus Q505F1
Anti Bait CoIP
18682553
种属间
Sumo1 P63166 PAX6 Homo sapiens P26367-1
Anti Bait CoIP
21084637
种属内
Sumo1 P63166 Ikzf1 Mus musculus Q03267
Anti Bait CoIP
15767674
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108702 ML-792 Inhibitor 99.90% 否
HY-139662 HB007 Inhibitor 99.73% 否
HY-RS14025 SUMO1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sumo1 NCBI NCBI:7341
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