2. Gene
  3. Vgll4 - vestigial like family member 4 Gene

Vgll4 - vestigial like family member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: VGL-4

基因 ID: 232334 | 基因类型: protein coding

关于 Vgll4

功能概要

Predicted to enable transcription coactivator binding activity. Involved in several processes, including negative regulation of cardiac muscle cell proliferation; negative regulation of hippo signaling; and positive regulation of cellular protein catabolic process. Located in nucleus. Is expressed in lung; submandibular gland primordium; tooth; and vibrissa. Orthologous to human VGLL4 (vestigial like family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Vgll4 基因产物(6)

mRNA Protein Name
NM_001356371.2 NP_001343300.1 transcription cofactor vestigial-like protein 4 isoform 2
NM_001411599.1 NP_001398528.1 transcription cofactor vestigial-like protein 4 isoform 2
NM_001411600.1 NP_001398529.1 transcription cofactor vestigial-like protein 4 isoform 3 precursor
NM_001411601.1 NP_001398530.1 transcription cofactor vestigial-like protein 4 isoform 4
NM_001411602.1 NP_001398531.1 transcription cofactor vestigial-like protein 4 isoform 5
NM_177683.4 NP_808351.1 transcription cofactor vestigial-like protein 4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15140898 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15140898 MGI
involved in negative regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
27720608 MGI
involved in negative regulation of hippo signaling IDA
IDA: 通过直接分析推断
27720608 MGI
involved in positive regulation of protein catabolic process IDA
IDA: 通过直接分析推断
27720608 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
15140898 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription cofactor vestigial-like protein 4

vestigial like 4

Vgll4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Vgll4 Q80V24 Tead4 Mus musculus Q62296
GMS
24525233
种属内
Vgll4 Q80V24 Tead4 Mus musculus Q62296
DLS
24525233
种属内
Vgll4 Q80V24 Tead4 Mus musculus Q62296
X-Ray Diffraction
24525233
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-137479 TEAD-IN-1 Inhibitor / 否
HY-RS15647 VGLL4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vgll4 NCBI NCBI:9686
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