1. Gene
  2. FST - Fst follistatin Gene

FST - Fst follistatin Gene

种属: Rattus norvegicus

同用名: FS; FOL1; Fst-288; RATFOL1

基因 ID: 24373 | 基因类型: protein coding

关于 FST

功能概要

Enables heparan sulfate proteoglycan binding activity. Predicted to be involved in hematopoietic progenitor cell differentiation; negative regulation of transcription by RNA polymerase II; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within several processes, including animal organ development; keratinocyte proliferation; and positive regulation of hair follicle development. Predicted to be located in cytoplasm and nucleus. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Orthologous to human FST (Follistatin). [provided by Alliance of Genome Resources, Apr 2022]

FST 基因产物(1)

mRNA Protein Name
NM_012561.3 NP_036693.1 follistatin precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparan sulfate proteoglycan binding IDA
IDA: 通过直接分析推断
12867435 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16482217 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to growth factor stimulus IEP
IEP: 通过表达模式推断
23567549 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
30599193 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

follistatin

activin-binding protein

follistatin-A

FST 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Fst P21674 INHBA Homo sapiens P08476
Chromatography
16482217
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens FST NCBI NCBI:10468
Mus musculus FST NCBI NCBI:14313