Il5 - interleukin 5 Gene

中文名称：白细胞介素 5

种属: Rattus norvegicus

关于 Il5

功能概要

该基因编码的蛋白可启动细胞因子活性和白细胞介素 5 受体结合活性。参与多个过程，包括 B 细胞增殖的正调节；嗜酸性粒细胞分化的正调节；以及通过 JAK-STAT 对受体信号通路的正向调控。位于细胞外空间。用于研究哮喘。多种疾病的生物标志物，包括过敏性鼻炎；食道癌;大脑中动脉梗塞;消化性食管炎;和前列腺肥大。该基因的人类直系同源物与哮喘有关。与人 IL5（白细胞介素 5）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cytokine activity and interleukin-5 receptor binding activity. Involved in several processes, including positive regulation of B cell proliferation; positive regulation of eosinophil differentiation; and positive regulation of receptor signaling pathway via JAK-STAT. Located in extracellular space. Used to study asthma. Biomarker of several diseases, including allergic rhinitis; esophageal cancer; middle cerebral artery infarction; peptic esophagitis; and prostatic hypertrophy. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL5 (interleukin 5). [provided by Alliance of Genome Resources, Apr 2022]