2. Gene
  3. Il5 - interleukin 5 Gene

Il5 - interleukin 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：白细胞介素 5

种属: Mus musculus

同用名: Il-5

基因 ID: 16191 | 基因类型: protein coding

关于 Il5

Chromosome 11: 53,611,621-53,615,933 forward strand.GRCm39:CM001004.3

This gene has 1 transcript (splice variant), 91 orthologues and is associated with 22 phenotypes. Low expression observed in reference dataset.

功能概要

该基因编码的蛋白可启动细胞因子活性。参与 DNA 结合转录因子活性的正调控；免疫球蛋白产生的正调节；和转录的正调控，DNA 模板。在肽酰酪氨酸磷酸化的正调节上游或正调节内起作用。位于细胞外空间。以冒号表示；胸腺;和胸腺原基。该基因的人类直系同源物与哮喘有关。与人 IL5（白细胞介素 5）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cytokine activity. Involved in positive regulation of DNA-binding transcription factor activity; positive regulation of immunoglobulin production; and positive regulation of transcription, DNA-templated. Acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in colon; thymus; and thymus primordium. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL5 (interleukin 5). [provided by Alliance of Genome Resources, Apr 2022]

Il5 基因产物(1)

mRNA Protein Name
NM_010558.1 NP_034688.1 interleukin-5 precursor

Il5 蛋白结构

IL5

IL5: pfam02025 (20 - 131)

  • 0
  • 100
  • 133 a.a.
蛋白主名 其他名称

interleukin-5

B-cell growth factor II

BCGF-II

T-cell replacing factor

TRF

cytotoxic T-lymphocyte inducer

eosinophil differentiation factor

重组 Il5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7081 IL-5 Protein, Mouse P04401 (M21-G133) ≥95%
HY-P7081A IL-5 Protein, Mouse (CHO) P04401 (M21-G133) ≥95%
HY-P70746 IL-5 Protein, Mouse (HEK293, His) P04401 (M21-G133) ≥95%
HY-P73219 IL-5 Protein, Mouse (sf9, His) P04401 (M21-G133) ≥95%
HY-P78155 IL-5 Protein, Mouse (Biotinylated, HEK293, His-Avi) P04401 (M21-G133) ≥95%
HY-P78314 IL-5 Protein, Mouse (HEK293, His-Avi) P04401 (M21-G133) ≥95%
HY-P700215AF Animal-Free IL-5 Protein, Mouse (His) P04401 (M21-G133) ≥95%

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-17002 Suplatast (Tosilate) Inhibitor 98.33% 否
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9945 Mepolizumab 98.00% 否
HY-P9923 Benralizumab 99.1% 否
HY-P9949 Reslizumab Antagonist 99.40% 否
Clinical Phase
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P9945A Mepolizumab (anti-IL5) 97.50% Phase 4
HY-P99371 Lirentelimab Inducer 99.91% Phase 3
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19969 YM-90709 Inhibitor 99.77% 否
HY-147660 IMMH001 Agonist 98.10% 否
HY-N8309 Luteolin-4'-O-glucoside Inhibitor 99.05% 否
HY-110295 SPL-334 Inhibitor / 否
HY-165484 AVP-13358 Inhibitor / 否
HY-19472 RWJ-58643 / 否
HY-19486 UR-1505 Inhibitor / 否
HY-P1111 Lyn peptide inhibitor Inhibitor / 否
HY-P1111A Lyn peptide inhibitor TFA Inhibitor / 否
HY-RS06770 IL5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06771 Il5 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06772 Il5 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06773 IL5RA Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P9923A Benralizumab (anti-IL5RA ) 99.60% 否
HY-P990058 Varokibart Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il5 NCBI NCBI:3567
Susscrofa domestica Il5 NCBI
Leporidae Il5 NCBI
Rattus norvegicus Il5 NCBI NCBI:24497
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