2. Gene
  3. Neto1 - neuropilin (NRP) and tolloid (TLL)-like 1 Gene

Neto1 - neuropilin (NRP) and tolloid (TLL)-like 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Btcl1; C130005O10Rik

基因 ID: 246317 | 基因类型: protein coding

关于 Neto1

功能概要

Enables ionotropic glutamate receptor binding activity. Involved in memory; regulation of long-term neuronal synaptic plasticity; and visual learning. Acts upstream of or within positive regulation of excitatory postsynaptic potential and receptor localization to synapse. Located in excitatory synapse and postsynaptic density membrane. Is integral component of postsynaptic density membrane. Is active in glutamatergic synapse. Is expressed in central nervous system; metencephalon lateral wall; and retina inner nuclear layer. Orthologous to human NETO1 (neuropilin and tolloid like 1). [provided by Alliance of Genome Resources, Apr 2022]

Neto1 基因产物(2)

mRNA Protein Name
NM_001360910.1 NP_001347839.1 neuropilin and tolloid-like protein 1 isoform 2
NM_144946.5 NP_659195.3 neuropilin and tolloid-like protein 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
21734292 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19243221 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterograde axonal transport of neurotransmitter receptor complex IDA
IDA: 通过直接分析推断
28680963 MGI
involved in anterograde axonal transport of neurotransmitter receptor complex IMP
IMP: 通过突变表型推断
28680963 MGI
involved in memory IMP
IMP: 通过突变表型推断
19243221 MGI
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
26720915 MGI
involved in neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: 通过突变表型推断
26720915 MGI
acts upstream of or within positive regulation of excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
21734292 MGI
acts upstream of or within receptor localization to synapse IMP
IMP: 通过突变表型推断
21734292 MGI
involved in regulation of long-term neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
19243221 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IDA
IDA: 通过直接分析推断
26720915 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IMP
IMP: 通过突变表型推断
26720915 MGI
involved in visual learning IMP
IMP: 通过突变表型推断
19243221 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
28680963 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
28680963 MGI
located in excitatory synapse IDA
IDA: 通过直接分析推断
19243221 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
19243221 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
19243221 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
19243221 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
19243221 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
19243221 MGI
is active in postsynaptic density membrane EXP
EXP: 通过实验结果推断
19243221 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
19243221 MGI
is active in postsynaptic density membrane IEP
IEP: 通过表达模式推断
19243221 MGI
is active in postsynaptic density membrane IMP
IMP: 通过突变表型推断
19243221 MGI
located in synapse IDA
IDA: 通过直接分析推断
21734292 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuropilin and tolloid-like protein 1

brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1

Neto1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Neto1 Q8R4I7 Dlg4 Mus musculus Q62108
Y2H
19243221
种属内
Neto1 Q8R4I7 Dlg4 Mus musculus Q62108
Anti Bait CoIP
19243221
种属间
Neto1 Q8R4I7 DLG4 Homo sapiens P78352
Anti Bait CoIP
19243221
种属间
Neto1 Q8R4I7 Grin2b Rattus norvegicus Q00960
Anti Bait CoIP
19243221
种属间
Neto1 Q8R4I7 Grin2a Rattus norvegicus Q00959
Anti Bait CoIP
19243221
种属间
Neto1 Q8R4I7 Grin2a Rattus norvegicus Q00959
Anti Tag CoIP
19243221
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09213 NETO1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Neto1 NCBI NCBI:81832
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