1. Gene
  2. Gip - gastric inhibitory polypeptide Gene

Gip - gastric inhibitory polypeptide Gene

种属: Rattus norvegicus

同用名: Gludins; RATGLUDINS

基因 ID: 25040 | 基因类型: protein coding

关于 Gip

功能概要

Enables signaling receptor binding activity. Involved in several processes, including positive regulation of cell communication; positive regulation of glucose transmembrane transport; and triglyceride homeostasis. Located in cytoplasm; extracellular space; and neuronal cell body. Used to study type 2 diabetes mellitus. Biomarker of hyperinsulinism; hypothyroidism; obesity; and pancreas disease. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human GIP (gastric inhibitory polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Gip 基因产物(1)

mRNA Protein Name
NM_019630.3 NP_062604.1 gastric inhibitory polypeptide precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor binding IMP
IMP: 通过突变表型推断
8958204 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in digestive system development IEP
IEP: 通过表达模式推断
8674860 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
7716131 RGD
involved in long-term synaptic potentiation IDA
IDA: 通过直接分析推断
18234983 RGD
involved in positive regulation of D-glucose transmembrane transport IMP
IMP: 通过突变表型推断
8843773 RGD
involved in positive regulation of cAMP/PKA signal transduction IMP
IMP: 通过突变表型推断
8958204 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
8958204 RGD
involved in positive regulation of synaptic transmission IDA
IDA: 通过直接分析推断
18234983 RGD
involved in response to acidic pH IMP
IMP: 通过突变表型推断
34554 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
6376308 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
19170165 RGD
involved in response to carbohydrate IEP
IEP: 通过表达模式推断
18685191 RGD
involved in response to glucose IEP
IEP: 通过表达模式推断
8931636 RGD
involved in response to lipid IEP
IEP: 通过表达模式推断
19520739 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19056762 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
6753106 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
7937351 RGD
involved in response to selenium ion IEP
IEP: 通过表达模式推断
11950233 RGD
involved in response to starvation IEP
IEP: 通过表达模式推断
7599968 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16402076 RGD
involved in triglyceride homeostasis IMP
IMP: 通过突变表型推断
1816061 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19520739 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
19170165 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

gastric inhibitory polypeptide

Glucose-dependent insulinotropic peptide

glucose-dependent insulinotropic polypeptide

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gip NCBI NCBI:2695
Macaca fascicularis Gip NCBI NCBI:102139187
Mus musculus Gip NCBI NCBI:14607
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