2. Gene
  3. Gip - gastric inhibitory polypeptide Gene

Gip - gastric inhibitory polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 14607 | 基因类型: protein coding

关于 Gip

功能概要

This gene encodes an incretin hormone that belongs to the glucagon superfamily. The encoded preproprotein undergoes proteolytic processing to generate mature Peptides that function as potent stimulators of Insulin secretion and inhibit gastric acid secretion. Transgenic mice overexpressing the encoded protein exhibit a significant increase in the expression of markers of bone formation, a decrease in the expression of markers of bone resorption and, an increase in the bone mass. [provided by RefSeq, Nov 2015]

Gip 基因产物(2)

mRNA Protein Name
NM_008119.2 NP_032145.2 gastric inhibitory polypeptide preproprotein
NM_008119.2 NP_032145.2 gastric inhibitory polypeptide preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables receptor ligand activity IDA
IDA: 通过直接分析推断
17971513 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
9075801 MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
33196462 MGI
acts upstream of or within adult locomotory behavior IDA
IDA: 通过直接分析推断
16822587 MGI
acts upstream of or within endocrine pancreas development IMP
IMP: 通过突变表型推断
21270265 MGI
acts upstream of or within exploration behavior IDA
IDA: 通过直接分析推断
16822587 MGI
acts upstream of or within memory IDA
IDA: 通过直接分析推断
16822587 MGI
involved in positive regulation of insulin secretion IDA
IDA: 通过直接分析推断
9075801 MGI
involved in positive regulation of insulin secretion IGI
IGI: 通过遗传相互作用推断
33196462 MGI
acts upstream of or within sensory perception of pain IDA
IDA: 通过直接分析推断
16822587 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

gastric inhibitory polypeptide

glucose-dependent insulinotropic polypeptide

重组 Gip 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77948 GIP Protein, Mouse (HEK293, His) P48756 (E22-Q85) ≥95%
HY-P77949 GIP Protein, Mouse (HEK293, Fc) P48756 (E22-Q85) ≥95%

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P10031A SAR441255 TFA Agonist 99.65% Phase 1
HY-P10031 SAR441255 Agonist / Phase 1
Pre-clinical Phase
生物活性分子 (27)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P0276 GIP, human Agonist 99.72% 否
HY-P2542 GIP (3-42), human Antagonist 99.98% 否
HY-P0276A GIP, human TFA Agonist 99.88% 否
HY-P2080B GIP (1-30) amide,human acetate Agonist 98.24% 否
HY-P10138A human GIP(3-30), amide TFA Antagonist 98.82% 否
HY-P3247 [D-Ala2]-GIP (human) Agonist 98.17% 否
HY-P3579 Gastric Inhibitory Peptide, porcine 99.67% 否
HY-P2541A GIP (1-30) amide, porcine TFA Agonist 99.95% 否
HY-P10138 human GIP(3-30), amide Antagonist 98.73% 否
HY-P3584A (Pro3) GIP, human TFA 99.79% 否
HY-P3580A Acetyl Gastric Inhibitory Peptide (human) (TFA) 99.70% 否
HY-P10302A GLP-1R/GIPR agonist-1 (soduim) Agonist 96.55% 否
HY-P10302 GLP-1R/GIPR agonist-1 Agonist / 否
HY-P2080C GIP (1-30)-Myr Agonist / 否
HY-P3255 DA-JC4 Agonist / 否
HY-P3584 (Pro3) GIP, human Agonist 99.79% 否
HY-153476 GIP/GLP-1 dual receptor agonist-1 Agonist / 否
HY-162513 DPP-4-IN-10 Inhibitor / 否
HY-E70397 Dipeptidyl peptidase IV / 否
HY-P1434 [Pro3]-GIP (mouse) Antagonist / 否
HY-P2080 GIP (1-30) amide,human Agonist / 否
HY-P2541 GIP (1-30) amide, porcine Agonist / 否
HY-P3577 [Tyr0] Gastric Inhibitory Peptide (23-42), human / 否
HY-P3578 Gastric Inhibitory Polypeptide (1-30), porcine Modulator / 否
HY-P3580 Acetyl Gastric Inhibitory Peptide (human) / 否
HY-RS05434 GIP Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-164535 Maridebart cafraglutide Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gip NCBI NCBI:2695
Macaca fascicularis Gip NCBI NCBI:102139187
Rattus norvegicus Gip NCBI NCBI:25040
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