1. Gene
  2. Slc5a1 - solute carrier family 5 member 1 Gene

Slc5a1 - solute carrier family 5 member 1 Gene

中文名称:溶质载体家族 5 成员 1

种属: Rattus norvegicus

同用名: SGLT1; SGLT1a

基因 ID: 25552 | 基因类型: protein coding

关于 Slc5a1

Primary_assembly 14: 77,553,843-77,618,547 reverse strand.mRatBN7.2:CM026987.1

This gene has 4 transcripts (splice variants), 248 orthologues, 13 paralogues and is associated with 4 phenotypes. Biased expression in Kidney (RPKM 121.6) and Lung (RPKM 51.7).

功能概要

该基因编码的蛋白可启动葡萄糖:钠同向转运体活性。预计参与多个过程,包括α-葡萄糖苷转运;跨质膜导入;和跨上皮水运输。预测作用于葡萄糖跨膜转运的上游或内部;肠道吸收;和后肾发育。位于顶端质膜;刷状缘膜;和细胞间连接。与人类 SLC5A1(溶质载体家族 5 成员 1)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables glucose:sodium symporter activity. Predicted to be involved in several processes, including alpha-glucoside transport; import across plasma membrane; and transepithelial water transport. Predicted to act upstream of or within glucose transmembrane transport; intestinal absorption; and metanephros development. Located in apical plasma membrane; brush border membrane; and cell-cell junction. Orthologous to human SLC5A1 (solute carrier family 5 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc5a1 基因产物(1)

mRNA Protein Name
NM_013033.2 NP_037165.1 sodium/glucose cotransporter 1

Slc5a1 蛋白结构

SLC5-6-like_sbd

SLC5-6-like_sbd: cl00456 (26 - 664)

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  • 665 a.a.
蛋白主名 其他名称

sodium/glucose cotransporter 1

Na(+)/glucose cotransporter 1

Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter)

high affinity sodium-glucose cotransporter

solute carrier family 5 (sodium/glucose cotransporter), member 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc5a1 NCBI NCBI:6523