1. Gene
  2. Sstr4 - somatostatin receptor 4 Gene

Sstr4 - somatostatin receptor 4 Gene

中文名称:生长抑素受体 4

种属: Rattus norvegicus

同用名: Smstr4

基因 ID: 25555 | 基因类型: protein coding

关于 Sstr4

Primary_assembly 3: 135,854,826-135,856,689 forward strand.mRatBN7.2:CM026976.1

This gene has 1 transcript (splice variant), 100 orthologues, 14 paralogues and is associated with 3 phenotypes.

功能概要

该基因编码的蛋白可启动生长抑素受体活性。参与多个过程,包括细胞对糖皮质激素刺激的反应;花生四烯酸分泌的正调节;和信号转导的调节。位于细胞质和质膜中。癫痫持续状态的生物标志物。与人类 SSTR4(生长抑素受体 4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables Somatostatin Receptor activity. Involved in several processes, including cellular response to glucocorticoid stimulus; positive regulation of arachidonic acid secretion; and regulation of signal transduction. Located in cytoplasm and plasma membrane. Biomarker of status epilepticus. Orthologous to human SSTR4 (Somatostatin Receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Sstr4 基因产物(1)

mRNA Protein Name
NM_013036.3 NP_037168.1 somatostatin receptor type 4
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17950729 RGD
enables somatostatin receptor activity IDA
IDA: 通过直接分析推断
1362243 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration IDA
IDA: 通过直接分析推断
17945410 RGD
involved in cell migration IMP
IMP: 通过突变表型推断
16534498 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
14512709 RGD
involved in forebrain development IEP
IEP: 通过表达模式推断
10805921 RGD
involved in negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
8175684 RGD
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
8175684 RGD
involved in positive regulation of arachidonate secretion IDA
IDA: 通过直接分析推断
8175684 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Sstr4 蛋白结构

7tmA_SSTR4

7tmA_SSTR4: cd15973 (43 - 317)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (44 - 70)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (77 - 103)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (114 - 144)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (156 - 178)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (203 - 232)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (247 - 277)

7tmA_SSTR4

7tmA_SSTR4: cd15973 (285 - 310)

  • 0
  • 100
  • 200
  • 300
  • 384 a.a.
蛋白主名 其他名称

somatostatin receptor type 4

SS-4-R

SS4-R

SS4R

Somatostatin receptor subtype 4 Rattus norvegicus Sprague-Dawley major hippocampal somatostatin receptor (SSTR4) mRNA

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sstr4 NCBI NCBI:6754