2. Gene
  3. Ddr1 - discoidin domain receptor tyrosine kinase 1 Gene

Ddr1 - discoidin domain receptor tyrosine kinase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：盘基蛋白结构域 受体酪氨酸激酶 1

种属: Rattus norvegicus

同用名: Cak; Drd1; PTK3D

基因 ID: 25678 | 基因类型: protein coding

关于 Ddr1

Primary_assembly 20: 3,044,320-3,064,468 forward strand.mRatBN7.2:CM026993.1

This gene has 2 transcripts (splice variants), 196 orthologues, 54 paralogues and is associated with 31 phenotypes. Biased expression in Kidney (RPKM 22.8), Brain (RPKM 117.8) and 8 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动胶原结合活性和蛋白酪氨酸激酶胶原受体活性。参与动物器官再生和皮肤发育。位于基底外侧质膜；画笔边框；和细胞质。充血性心力衰竭的生物标志物。该基因的人类直系同源物与肺非小细胞癌有关。与人类 DDR1（盘状蛋白结构域受体酪氨酸激酶 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable collagen binding activity and protein tyrosine kinase collagen receptor activity. Involved in animal organ regeneration and skin development. Located in basolateral plasma membrane; brush border; and cytoplasm. Biomarker of congestive heart failure. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human DDR1 (Discoidin Domain Receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ddr1 基因产物(2)

mRNA Protein Name
NM_013137.2 NP_037269.2 epithelial discoidin domain-containing receptor 1 precursor
NM_001166022.1 NP_001159494.1 epithelial discoidin domain-containing receptor 1 precursor

Ddr1 蛋白结构

FA58C

FA58C: cd00057 (57 - 184)

PTKc_DDR1

PTKc_DDR1: cd05096 (600 - 903)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 910 a.a.
蛋白主名 其他名称

epithelial discoidin domain-containing receptor 1

CD167 antigen-like family member A

cell adhesion kinase

discoidin domain receptor family, member 1

discoidin receptor tyrosine kinase

epithelial discoidin domain receptor 1

neurotrophic tyrosine kinase receptor type 4

protein-tyrosine kinase 3

protein-tyrosine kinase PTK-3

tyrosine kinase DDR

tyrosine-protein kinase CAK

重组 Ddr1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75299 DDR1 Protein, Rat (HEK293, His) Q6MG19 (D22-T413) ≥95%
HY-P75300 DDR1 Protein, Rat (HEK293, hFc) Q6MG19 (D20-T413) ≥95%

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-16961 Sitravatinib Inhibitor 99.57% Phase 3
HY-16961A Sitravatinib malate Inhibitor / Phase 3
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135401 VU6015929 Inhibitor 99.50% 否
HY-133670 DDR1-IN-6 Inhibitor 98.16% 否
HY-114173 DDR1-IN-4 Inhibitor 98.19% 否
HY-133669 DDR1-IN-5 Inhibitor 99.27% 否
HY-156552 DDR1/2 inhibitor-2 Inhibitor 99.73% 否
HY-162102 DDR1-IN-8 Inhibitor / 否
HY-13979A DDR1-IN-1 dihydrochloride Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ddr1 NCBI NCBI:780
Mus musculus Ddr1 NCBI NCBI:12305
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