2. Gene
  3. BOD1L1 - biorientation of chromosomes in cell division 1 like 1 Gene

BOD1L1 - biorientation of chromosomes in cell division 1 like 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞分裂中染色体的生物定向 1 样 1

种属: Homo sapiens

同用名: BOD1L; FAM44A

基因 ID: 259282 | 基因类型: protein coding

关于 BOD1L1

Cytogenetic location: 4p15.33 Genomic coordinates (GRCh38): 4:13,568,738-13,627,725 (from NCBI)

This gene has 6 transcripts (splice variants), 208 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 8.2), testis (RPKM 7.4) and 25 other tissues.

功能概要

预测可启用蛋白磷酸酶 2A 结合活性和蛋白磷酸酶抑制剂活性。参与细胞对 DNA 损伤刺激的反应和复制叉处理。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein Phosphatase 2A binding activity and protein Phosphatase Inhibitor activity. Involved in cellular response to DNA damage stimulus and replication fork processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

BOD1L1 基因产物(1)

mRNA Protein Name
NM_148894.3 NP_683692.2 biorientation of chromosomes in cell division protein 1-like 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24981860 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IDA
IDA: 通过直接分析推断
26166705 GOA
involved in replication fork processing IDA
IDA: 通过直接分析推断
26166705 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Set1C/COMPASS complex IPI
IPI: 通过物理相互作用推断
23508102 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BOD1L1 蛋白结构

COMPASS-Shg1

COMPASS-Shg1: COMPASS (Complex proteins associated with Set1p) component shg1 (57 - 159)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 3051 a.a.
蛋白主名 其他名称

biorientation of chromosomes in cell division protein 1-like 1

biorientation of chromosomes in cell division 1-like

BOD1L1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra BOD1L1 Q8NFC6 WDR5 Homo sapiens P61964
Anti Bait CoIP
24981860
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Schimke Immunoosseous Dysplasia

Schimke Immuno-Osseous Dysplasia

SIOD

Immunoosseous Dysplasia, Schimke Type

Schimke Syndrome

Immunoosseous Dysplasia Schimke Type

Spondyloepiphyseal Dysplasia - Nephrotic Syndrome

Spondyloepiphyseal Dysplasia Nephrotic Syndrome

Spondyloepiphyseal Dysplasia-Nephrotic Syndrome
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01569 BOD1L1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris BOD1L1 VGNC VGNC:38496
Felis catus BOD1L1 VGNC VGNC:78458
Bos taurus BOD1L1 VGNC VGNC:26537
Rattus norvegicus BOD1L1 RGD RGD:621413
Macaca mulatta BOD1L1 VGNC VGNC:97741
Mus musculus BOD1L1 MGD MGI:2444804
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z