2. Gene
  3. Esrrg - estrogen-related receptor gamma Gene

Esrrg - estrogen-related receptor gamma Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：雌激素相关受体 γ

种属: Mus musculus

同用名: ERR3; Errg; NR3B3; mKIAA0832

基因 ID: 26381 | 基因类型: protein coding

关于 Esrrg

Chromosome 1: 187,340,988-187,947,082 forward strand.GRCm39:CM000994.3

This gene has 5 transcripts (splice variants), 136 orthologues, 8 paralogues and is associated with 23 phenotypes. Biased expression in cerebellum adult (RPKM 6.9), kidney adult (RPKM 4.9) and 12 other tissues.

功能概要

该基因编码的蛋白可启动 DNA 结合转录激活因子活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 转录调节区序列特异性 DNA 结合活性。参与冷诱导产热的正调节和 RNA 聚合酶 II 转录的正调节。以多种结构表达，包括中枢神经系统；泌尿生殖系统；直觉;心;和感觉器官。与人类 ESRRG（雌激素相关受体γ）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart; and sensory organ. Orthologous to human ESRRG (estrogen related receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

Esrrg 基因产物(5)

mRNA Protein Name
NM_011935.3 NP_036065.1 estrogen-related receptor gamma isoform1
NM_001357536.1 NP_001344465.1 estrogen-related receptor gamma isoform 3
NM_001357534.1 NP_001344463.1 estrogen-related receptor gamma isoform 2
NM_001243792.1 NP_001230721.1 estrogen-related receptor gamma isoform 2
NM_001357535.1 NP_001344464.1 estrogen-related receptor gamma isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
10428842 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
15149736 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15149736 MGI
enables estrogen response element binding IDA
IDA: 通过直接分析推断
10428842 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10428842 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12715898 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
17229846 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10428842 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
15149736 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Esrrg 蛋白结构

NR_DBD_ERR

NR_DBD_ERR: cd07170 (121 - 217)

NR_LBD_ERR

NR_LBD_ERR: cd06946 (236 - 455)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 458 a.a.
蛋白主名 其他名称

estrogen-related receptor gamma

estrogen receptor-related protein 3

estrogen-related receptor 3

nuclear receptor subfamily 3 group B member 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04543 ESRRG Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04544 Esrrg Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04545 Esrrg Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Esrrg NCBI NCBI:2104
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