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  2. Git2 - GIT ArfGAP 2 Gene

Git2 - GIT ArfGAP 2 Gene

种属: Mus musculus

同用名: CAT2; mKIAA0148; 1500036H07Rik; 5830420E16Rik; 6430510B20Rik; 9630056M03Rik; B230104M05Rik

基因 ID: 26431 | 基因类型: protein coding

关于 Git2

功能概要

Predicted to enable GTPase activator activity and metal ion binding activity. Involved in presynaptic modulation of chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Acts upstream of or within behavioral response to pain. Is active in calyx of Held. Is expressed in genitourinary system. Orthologous to human GIT2 (GIT ArfGAP 2). [provided by Alliance of Genome Resources, Apr 2022]

Git2 基因产物(4)

mRNA Protein Name
NM_001077359.1 NP_001070827.1 ARF GTPase-activating protein GIT2 isoform 2
NM_001077360.1 NP_001070828.1 ARF GTPase-activating protein GIT2 isoform 3
NM_001347400.1 NP_001334329.1 ARF GTPase-activating protein GIT2 isoform 4
NM_019834.3 NP_062808.3 ARF GTPase-activating protein GIT2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
17310244 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within behavioral response to pain IMP
IMP: 通过突变表型推断
23870131 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
26637799 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
26637799 MGI
involved in regulation of synaptic vesicle exocytosis IDA
IDA: 通过直接分析推断
26637799 MGI
involved in regulation of synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
26637799 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in calyx of Held IDA
IDA: 通过直接分析推断
26637799 MGI
is active in calyx of Held IMP
IMP: 通过突变表型推断
26637799 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
26637799 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ARF GTPase-activating protein GIT2

ARF GAP GIT2

ARF GTPase activating protein 2

G protein-coupled receptor kinase-interactor 2

GRK-interacting protein 2

cool-interacting tyrosine-phosphorylated protein 2

Git2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Git2 Q9JLQ2 Arhgef7 Mus musculus Q9ES28
Y2H
15102471
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Git2 NCBI NCBI:9815