2. Gene
  3. Nrip1 - nuclear receptor interacting protein 1 Gene

Nrip1 - nuclear receptor interacting protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RIP140; 9630050P12; 6030458L20Rik; 8430438I05Rik

基因 ID: 268903 | 基因类型: protein coding

关于 Nrip1

功能概要

Enables several functions, including histone deacetylase binding activity; retinoid X receptor binding activity; and transcription coactivator activity. Involved in circadian regulation of gene expression; lipid storage; and ovarian follicle rupture. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nuclear speck. Part of histone deacetylase complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in CAKUT and osteoporosis. Orthologous to human NRIP1 (nuclear receptor interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Nrip1 基因产物(2)

mRNA Protein Name
NM_001358238.1 NP_001345167.1 nuclear receptor-interacting protein 1
NM_173440.3 NP_775616.1 nuclear receptor-interacting protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
11006275 MGI
enables nuclear retinoic acid receptor binding IPI
IPI: 通过物理相互作用推断
10531331 MGI
enables nuclear retinoid X receptor binding IPI
IPI: 通过物理相互作用推断
10531331 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9774688 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
9774688 MGI
enables transcription coactivator activity IDA
IDA: 通过直接分析推断
21628546 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
9774688 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian regulation of gene expression IMP
IMP: 通过突变表型推断
21628546 MGI
involved in lipid storage IMP
IMP: 通过突变表型推断
15155905 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9774688 MGI
involved in ovarian follicle rupture IMP
IMP: 通过突变表型推断
15919748 MGI
involved in ovulation IMP
IMP: 通过突变表型推断
11100122 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19796622 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of histone deacetylase complex IPI
IPI: 通过物理相互作用推断
11278635 MGI
located in nuclear speck IDA
IDA: 通过直接分析推断
23071095 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15879431 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nuclear receptor-interacting protein 1

nuclear factor RIP140

receptor-interacting protein 140

Nrip1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Nrip1 Q8CBD1 HDAC3 Homo sapiens O15379
Anti Tag CoIP
11006275
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09571 NRIP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nrip1 NCBI NCBI:8204
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