BEX3 - brain expressed X-linked 3 Gene

中文名称：脑表达 X-连锁 3

种属: Homo sapiens

同用名: Bex; NADE; HGR74; NGFRAP1; DXS6984E

基因 ID: 27018 | 基因类型: protein coding

关于 BEX3

Cytogenetic location: Xq22.2 Genomic coordinates (GRCh38): X:103,376,323-103,378,164 (from NCBI)

This gene has 4 transcripts (splice variants), 90 orthologues and 3 paralogues. Broad expression in brain (RPKM 147.0), ovary (RPKM 108.9) and 24 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与信号转导。预计通过死亡域受体作用于外在凋亡信号通路的上游或内部。位于胞质溶胶中。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within extrinsic apoptotic signaling pathway via death domain receptors. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

BEX3 基因产物(4)

mRNA	Protein	Name
NM_001282674.1	NP_001269603.1	protein BEX3 isoform c
NM_014380.3	NP_055195.1	protein BEX3 isoform b
NM_206915.3	NP_996798.1	protein BEX3 isoform b
NM_206917.3	NP_996800.1	protein BEX3 isoform a

BEX3 蛋白结构

BEX

0
100
111 a.a.

蛋白主名

其他名称

protein BEX3

brain-expressed X-linked protein 3

BEX3 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	BEX3	Q00994	NECAB2	Homo sapiens	Q7Z6G3-2	Validated Y2H	25416956
种属内	BEX3	Q00994	NECAB2	Homo sapiens	Q7Z6G3-2	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	NECAB2	Homo sapiens	Q7Z6G3-2	Validated Y2H	32296183
种属内	BEX3	Q00994	NECAB2	Homo sapiens	Q7Z6G3-2	Y2H Array	32296183
种属内	BEX3	Q00994	GOLGA8F	Homo sapiens	Q08AF8	Validated Y2H	25416956
种属内	BEX3	Q00994	GOLGA8F	Homo sapiens	Q08AF8	Y2H Array	25416956
种属内	BEX3	Q00994	GOLGA8DP	Homo sapiens	Q0D2H9	Y2H Array	25416956
种属内	BEX3	Q00994	BFSP2	Homo sapiens	Q13515	Validated Y2H	32296183
种属内	BEX3	Q00994	TSC1	Homo sapiens	Q92574	Y2H	17355907
种属内	BEX3	Q00994	TSC1	Homo sapiens	Q92574	Confocal	17355907
种属内	BEX3	Q00994	KRT34	Homo sapiens	O76011	Y2H Array	32296183
种属内	BEX3	Q00994	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	DMWD	Homo sapiens	G5E9A7	Validated Y2H	32814053
种属内	BEX3	Q00994	DMWD	Homo sapiens	G5E9A7	Y2H Pooling	32814053
种属内	BEX3	Q00994	DMWD	Homo sapiens	G5E9A7	Y2H Array	32814053
种属内	BEX3	Q00994	CBY2	Homo sapiens	Q8NA61-2	Y2H Array	32296183
种属内	BEX3	Q00994	CBY2	Homo sapiens	Q8NA61-2	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	CBY2	Homo sapiens	Q8NA61-2	Validated Y2H	32296183
种属内	BEX3	Q00994	EMILIN1	Homo sapiens	Q9Y6C2-2	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	EMILIN1	Homo sapiens	Q9Y6C2-2	Validated Y2H	32296183
种属内	BEX3	Q00994	EMILIN1	Homo sapiens	Q9Y6C2-2	Y2H Array	32296183
种属内	BEX3	Q00994	MCCD1	Homo sapiens	P59942	Y2H Array	32296183
种属内	BEX3	Q00994	MCCD1	Homo sapiens	P59942	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	S100Z	Homo sapiens	Q8WXG8	Validated Y2H	32296183
种属内	BEX3	Q00994	S100Z	Homo sapiens	Q8WXG8	Y2H Array	32296183
种属内	BEX3	Q00994	S100Z	Homo sapiens	Q8WXG8	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	GLE1	Homo sapiens	Q53GS7	Validated Y2H	32814053
种属内	BEX3	Q00994	GLE1	Homo sapiens	Q53GS7	Y2H Array	32814053
种属内	BEX3	Q00994	TSNAX	Homo sapiens	Q99598	Y2H Array	32296183
种属内	BEX3	Q00994	TSNAX	Homo sapiens	Q99598	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	TSNAX	Homo sapiens	Q99598	Validated Y2H	32296183
种属内	BEX3	Q00994	TACC3	Homo sapiens	Q9Y6A5	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	TACC3	Homo sapiens	Q9Y6A5	Validated Y2H	32296183
种属内	BEX3	Q00994	TACC3	Homo sapiens	Q9Y6A5	Y2H Array	32296183
种属内	BEX3	Q00994	ING4	Homo sapiens	Q9UNL4	Validated Y2H	32296183
种属内	BEX3	Q00994	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
种属内	BEX3	Q00994	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
种属内	BEX3	Q00994	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
种属内	BEX3	Q00994	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
种属内	BEX3	Q00994	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
种属内	BEX3	Q00994	HRAS	Homo sapiens	P01112	Y2H Array	32814053
种属内	BEX3	Q00994	SMARCD1	Homo sapiens	Q96GM5	Validated Y2H	32296183
种属内	BEX3	Q00994	ING5	Homo sapiens	Q8WYH8	Validated Y2H	32296183
种属内	BEX3	Q00994	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
种属内	BEX3	Q00994	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
种属内	BEX3	Q00994	FSD2	Homo sapiens	A1L4K1	Validated Y2H	25416956
种属内	BEX3	Q00994	FSD2	Homo sapiens	A1L4K1	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	FSD2	Homo sapiens	A1L4K1	Y2H Array	32296183
种属内	BEX3	Q00994	MDFI	Homo sapiens	Q99750	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	MDFI	Homo sapiens	Q99750	Validated Y2H	32296183
种属内	BEX3	Q00994	MDFI	Homo sapiens	Q99750	Y2H Array	32296183
种属内	BEX3	Q00994	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	25416956
种属内	BEX3	Q00994	USHBP1	Homo sapiens	Q8N6Y0	Validated Y2H	25416956
种属内	BEX3	Q00994	USHBP1	Homo sapiens	Q8N6Y0	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	USHBP1	Homo sapiens	Q8N6Y0	Validated Y2H	32296183
种属内	BEX3	Q00994	USHBP1	Homo sapiens	Q8N6Y0	Y2H Array	32296183
种属内	BEX3	Q00994	ZNF417	Homo sapiens	Q8TAU3	Validated Y2H	32296183
种属内	BEX3	Q00994	BEX3	Homo sapiens	Q00994	Y2H Array	25416956
种属内	BEX3	Q00994	BEX3	Homo sapiens	Q00994	Y2H Array	32296183
种属内	BEX3	Q00994	CCDC116	Homo sapiens	Q8IYX3	Validated Y2H	25416956
种属内	BEX3	Q00994	BEX3	Homo sapiens	Q00994	Validated Y2H	32296183
种属内	BEX3	Q00994	BEX3	Homo sapiens	Q00994	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	S100A1	Homo sapiens	P23297	Y2H Array	32296183
种属内	BEX3	Q00994	S100A1	Homo sapiens	P23297	Y2H Prey Pooling	32296183
种属内	BEX3	Q00994	ENKD1	Homo sapiens	Q9H0I2	Validated Y2H	32296183
种属内	BEX3	Q00994	EMILIN1	Homo sapiens	Q9Y6C2	Y2H Prey Pooling	25416956
种属内	BEX3	Q00994	EMILIN1	Homo sapiens	Q9Y6C2	Validated Y2H	25416956
种属内	BEX3	Q00994	CTNNBL1	Homo sapiens	Q8WYA6	Y2H Array	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Cogan-Reese Syndrome

Joubert Syndrome 1

Joubert Syndrome	Jbts
Cerebellooculorenal Syndrome 1	JBTS1
Joubert-Boltshauser Syndrome	Cerebelloparenchymal Disorder Iv
Cpd4	Cors1
Joubert Syndrome And Related Disorders	Jsrd
Familial Aplasia Of The Vermis	Joubert Syndrome Related Disorders
Js	Cerebellar Vermis Agenesis
Cerebelloparenchymal Disorder 4	Agenesis Of Cerebellar Vermis
Cerebello-Oculo-Renal Syndrome	Cors
Joubert-Bolthauser Syndrome	Cpd Iv
Classic Joubert Syndrome	Joubert Syndrome Type A
Pure Joubert Syndrome	Cerebello-Oculo-Renal Syndrome 1
Joubert Syndrome-1	Joubert Syndrome, Type 1
Joubert'S Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS01482	BEX3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	BEX3	VGNC	VGNC:54665
Bos taurus	BEX3	VGNC	VGNC:50552
Rattus norvegicus	BEX3	RGD	RGD:3148
Mus musculus	BEX3	MGD	MGI:1338016

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4