CTNNBL1 - catenin beta like 1 Gene

中文名称：连环蛋白β样 1

种属: Homo sapiens

同用名: NAP; P14L; IMD99; PP8304; C20orf33; dJ633O20.1

关于 CTNNBL1

功能概要

该基因编码的蛋白质是前体 mRNA 加工因子 19 细胞分裂周期 5 样 (PRP19-CDC5L) 蛋白复合物的组成部分，它激活前体 mRNA 剪接，是剪接体的组成部分。编码的蛋白质也是一种核定位序列结合蛋白，与激活诱导的脱氨酶结合，对抗体多样化很重要。该基因也可能与肥胖的发展有关。可变剪接导致多个转录本变体。该基因的假基因已在 X 染色体上定义。[RefSeq 提供，2013 年 7 月]

The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]