PPP2R3B - protein phosphatase 2 regulatory subunit B''beta Gene

中文名称：蛋白磷酸酶 2 调节亚基 B''beta

种属: Homo sapiens

同用名: PR48; PR70; NYREN8; PPP2R3L; PPP2R3LY

关于 PPP2R3B

功能概要

蛋白磷酸酶 2 (以前称为 2A 型) 是四种主要的 Ser/Thr 磷酸酶之一，与细胞生长和分裂的负调控有关。蛋白磷酸酶 2 全酶是由结构亚基 A、催化亚基 C 和调节亚基 B 组成的异源三聚体蛋白。调节亚基由一组不同的基因编码，这些基因被分为 B/PR55、B'/PR61 和 B''/PR72 家族。这些不同的调节亚基赋予全酶不同的酶特异性和细胞内定位。该基因的产物属于 B''家族。 B''家族进一步分为亚科。该基因的产物属于调节亚基 B''的β亚家族。[RefSeq 提供，2010 年 4 月]

Protein Phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein Phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010]