1. Gene
  2. GPX7 - glutathione peroxidase 7 Gene

GPX7 - glutathione peroxidase 7 Gene

中文名称:谷胱甘肽过氧化物酶 7

种属: Homo sapiens

同用名: GPX6; CL683; GPx-7; NPGPx; GSHPx-7

基因 ID: 2882 | 基因类型: protein coding

关于 GPX7

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:52,602,371-52,609,051 (from NCBI)

This gene has 2 transcripts (splice variants), 204 orthologues and 7 paralogues. Ubiquitous expression in placenta (RPKM 15.6), thyroid (RPKM 9.2) and 24 other tissues.

功能概要

启用过氧化氢酶活性。预计参与细胞对氧化应激的反应。位于内质网。 [由基因组资源联盟提供,2022 年 4 月]

Enables catalase activity. Predicted to be involved in cellular response to oxidative stress. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

GPX7 基因产物(1)

mRNA Protein Name
NM_015696.5 NP_056511.2 glutathione peroxidase 7 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables catalase activity IDA
IDA: 通过直接分析推断
22157330 GOA
enables peroxidase activity EXP
EXP: 通过实验结果推断
21215271 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
21215271 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GPX7 蛋白结构

GSHPx

GSHPx: Glutathione peroxidase (25 - 132)

  • 0
  • 100
  • 187 a.a.
蛋白主名 其他名称

glutathione peroxidase 7

glutathione peroxidase 6

GPX7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GPX7 Q96SL4 CPNE7 Homo sapiens Q9UBL6-2 32296183
种属内
GPX7 Q96SL4 GET3 Homo sapiens O43681 25416956
种属内
GPX7 Q96SL4 GET3 Homo sapiens O43681 25416956
种属内
GPX7 Q96SL4 SGTA Homo sapiens O43765 16189514
种属内
GPX7 Q96SL4 SPRED1 Homo sapiens Q7Z699 32814053
种属内
GPX7 Q96SL4 SPRED1 Homo sapiens Q7Z699 32814053
种属内
GPX7 Q96SL4 SPRED1 Homo sapiens Q7Z699 32814053
种属内
GPX7 Q96SL4 CEP70 Homo sapiens Q8NHQ1 25416956
种属内
GPX7 Q96SL4 TCF25 Homo sapiens Q9BQ70 32296183
种属内
GPX7 Q96SL4 UBQLN2 Homo sapiens Q9UHD9 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 GPX7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75798 GPX7 Protein, Human (HEK293, Fc) Q96SL4/NP_056511.2 (Q20-L187) ≥95%

关联疾病

疾病名称 别名
Barrett Esophagus

Barrett'S Esophagus

Barrett Esophagus/Esophageal Adenocarcinoma

Barrett Metaplasia

Barrett'S Ulcer Of Esophagus

Ulcerative Esophagitis

Barrett'S Esophagus With Esophagitis

Barrett'S Oesophagus

Barretts Syndrome

Barrett Syndrome

BE

Peptic Ulcer Of Esophagus

Adenocarcinoma Of Esophagus

Gastroesophageal Reflux

Gastroesophageal Reflux Disease

Gerd

GER

Gastroesophageal Reflux, Pediatric

Acid Reflux

Gastresophageal Reflux

Gastro-Esophageal Reflux

Gerd - Gastro-Esophageal Reflux Disease

Barrett'S Adenocarcinoma

Barrett Adenocarcinoma

Adenocarcinoma Arising In Barrett'S Mucosa

Esophagus Adenocarcinoma

Esophageal Adenocarcinoma

Oesophageal Adenocarcinoma

Adenocarcinoma Of Esophagus

Adenocarcinoma Of The Esophagus

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GPX7 RGD RGD:1306999
Macaca mulatta GPX7 VGNC VGNC:73155
Felis catus GPX7 VGNC VGNC:67454
Bos taurus GPX7 VGNC VGNC:29621
Mus musculus GPX7 MGD MGI:1914555
Others GPX7 NCBI