2. Gene
  3. MAGEH1 - MAGE family member H1 Gene

MAGEH1 - MAGE family member H1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：MAGE 家族成员 H1

种属: Homo sapiens

同用名: APR1; APR-1; MAGEH

基因 ID: 28986 | 基因类型: protein coding

关于 MAGEH1

Cytogenetic location: Xp11.21 Genomic coordinates (GRCh38): X:55,452,127-55,453,566 (from NCBI)

This gene has 1 transcript (splice variant), 170 orthologues and 37 paralogues.

功能概要

该基因属于黑色素瘤相关抗原 (MAGE) 超家族的非 CT (非癌症/睾丸) 亚组。编码的蛋白质可能与细胞凋亡、细胞周期停滞、生长抑制或细胞分化有关。该蛋白可能通过 STAT1-alpha (信号转导和转录激活因子 1-alpha) 通路参与 atRA (全反式视黄酸) 信号传导。[RefSeq 提供，2013 年 8 月]

This gene belongs to the non-CT (non Cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with Apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]

MAGEH1 基因产物(1)

mRNA Protein Name
NM_014061.5 NP_054780.2 melanoma-associated antigen H1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MAGEH1 蛋白结构

MAGE

MAGE: MAGE family (60 - 176)

  • 0
  • 100
  • 200
  • 219 a.a.
蛋白主名 其他名称

melanoma-associated antigen H1

apoptosis-related protein 1

MAGEH1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MAGEH1 Q9H213 SH2B2 Homo sapiens O14492-2
Y2H Array
32296183
Intra MAGEH1 Q9H213 SH2B2 Homo sapiens O14492-2
Y2H Prey Pooling
32296183
Intra MAGEH1 Q9H213 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
25416956
Intra MAGEH1 Q9H213 HMBOX1 Homo sapiens Q6NT76
Y2H Array
25416956
Intra MAGEH1 Q9H213 TNIP1 Homo sapiens Q15025
Validated Y2H
25416956
Intra MAGEH1 Q9H213 TNIP1 Homo sapiens Q15025
Y2H Array
25416956
Intra MAGEH1 Q9H213 TNIP1 Homo sapiens Q15025
Y2H Prey Pooling
25416956
Intra MAGEH1 Q9H213 YWHAG Homo sapiens P61981
Y2H Array
32814053
Intra MAGEH1 Q9H213 YWHAG Homo sapiens P61981
Validated Y2H
32814053
Intra MAGEH1 Q9H213 YWHAG Homo sapiens P61981
Y2H Pooling
32814053
Intra MAGEH1 Q9H213 TRIM41 Homo sapiens Q8WV44
Validated Y2H
25416956
Intra MAGEH1 Q9H213 TRIM41 Homo sapiens Q8WV44
Y2H Prey Pooling
25416956
Intra MAGEH1 Q9H213 ZSCAN9 Homo sapiens O15535
Y2H Array
25416956
Intra MAGEH1 Q9H213 SETDB1 Homo sapiens Q15047-2
Y2H Array
32814053
Intra MAGEH1 Q9H213 SETDB1 Homo sapiens Q15047-2
Y2H Pooling
32814053
Intra MAGEH1 Q9H213 SETDB1 Homo sapiens Q15047-2
Validated Y2H
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Necatoriasis

Miner'S Anaemia

Negro Cachexia

Dochmiasis

Ground Itch Disease

Brickmaker'S Chlorosis

Coolie Itch Anaemia

Cachexia Aquosa

Dew Itch Anaemia

Brickmaker'S Anaemia

Tunnel Worker'S Anaemia

Egyptian Anaemia

Tunnel Worker'S Disease

Miner'S Cachexia

Greisinger Disease

Tropical Chlorosis

Egyptian Chlorosis

Tunnel Anaemia

Dochmiosis

Necatorosis

African Cachexia

Water Itch Anaemia

Infection Due To Necator Americanus

St Gotthard Disease

Gotthard Tunnel Disease
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Ostertagiasis
Ascaris Lumbricoides Infection

Ascariasis

Ascaris Lumbricoides Infection, Susceptibility To

Ascariasis, Susceptibility To

Ascariasis - Roundworm

Infection Due To Ascaris Lumbricoides

Ascaridiasis

Roundworm Infection

Ascaridia

Ascaridiosis

Ascaridosis

Ascariosis

Ascaris

Ascaris Lumbricoides Infestation

Ascaris Infection

Infection By Ascaridia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07979 MAGEH1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MAGEH1 VGNC VGNC:42926
Bos taurus MAGEH1 VGNC VGNC:31145
Mus musculus MAGEH1 MGD MGI:1922875
Rattus norvegicus MAGEH1 RGD RGD:1359316
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