1. Gene
  2. Cd36 - CD36 molecule Gene

Cd36 - CD36 molecule Gene

种属: Rattus norvegicus

同用名: Fat; RGD1562323

基因 ID: 29184 | 基因类型: protein coding

关于 Cd36

功能概要

Enables several functions, including oleic acid binding activity; scavenger receptor activity; and thrombospondin receptor activity. Involved in several processes, including fatty acid metabolic process; positive regulation of macromolecule metabolic process; and response to peptide hormone. Located in several cellular components, including brush border membrane; caveola; and sarcolemma. Part of protein-containing complex. Used to study interstitial lung disease (multiple); macular degeneration; myocardial infarction; obesity; and polycystic ovary syndrome. Biomarker of artery disease (multiple); hypertrophic cardiomyopathy; nephrosis; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; pulmonary tuberculosis; and type 2 diabetes mellitus. Orthologous to human CD36 (CD36 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd36 基因产物(1)

mRNA Protein Name
NM_031561.2 NP_113749.2 platelet glycoprotein 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables oleic acid binding IDA
IDA: 通过直接分析推断
8320718 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15161924 RGD
enables scavenger receptor activity IMP
IMP: 通过突变表型推断
18941241 RGD
enables thrombospondin receptor activity IDA
IDA: 通过直接分析推断
10487979 RGD
enables transforming growth factor beta binding IDA
IDA: 通过直接分析推断
10487979 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in amyloid-beta clearance by cellular catabolic process IMP
IMP: 通过突变表型推断
18941241 RGD
involved in cell-cell adhesion via plasma-membrane adhesion molecules IEP
IEP: 通过表达模式推断
24317495 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
19273501 RGD
involved in digestive tract development IEP
IEP: 通过表达模式推断
11595646 RGD
involved in eating behavior IMP
IMP: 通过突变表型推断
25477422 RGD
involved in energy homeostasis IMP
IMP: 通过突变表型推断
23557700 RGD
involved in fatty acid metabolic process IDA
IDA: 通过直接分析推断
11729182 RGD
involved in fatty acid metabolic process IMP
IMP: 通过突变表型推断
11175782 RGD
involved in fatty acid oxidation IMP
IMP: 通过突变表型推断
15161924 RGD
involved in fatty acid transport IDA
IDA: 通过直接分析推断
14748718 RGD
involved in fatty acid transport IEP
IEP: 通过表达模式推断
16684853 RGD
involved in fatty acid transport IMP
IMP: 通过突变表型推断
15331529 RGD
involved in long-chain fatty acid metabolic process IMP
IMP: 通过突变表型推断
15161924 RGD
involved in long-chain fatty acid transport IMP
IMP: 通过突变表型推断
9315741 RGD
involved in maternal placenta development IEP
IEP: 通过表达模式推断
24391823 RGD
involved in negative regulation of angiogenesis IMP
IMP: 通过突变表型推断
18772338 RGD
involved in negative regulation of systemic arterial blood pressure IMP
IMP: 通过突变表型推断
22128087 RGD
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
20075072 RGD
involved in positive regulation of glycogen biosynthetic process IDA
IDA: 通过直接分析推断
14640889 RGD
involved in positive regulation of phagocytosis IMP
IMP: 通过突变表型推断
23238794 RGD
involved in positive regulation of triglyceride metabolic process IDA
IDA: 通过直接分析推断
23099442 RGD
involved in receptor-mediated endocytosis IMP
IMP: 通过突变表型推断
18941241 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
17374701 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
17640331 RGD
involved in response to fatty acid IDA
IDA: 通过直接分析推断
21610069 RGD
involved in response to fatty acid IMP
IMP: 通过突变表型推断
23557700 RGD
involved in response to growth hormone IEP
IEP: 通过表达模式推断
17640331 RGD
involved in response to lipid IMP
IMP: 通过突变表型推断
21610069 RGD
involved in response to mechanical stimulus IMP
IMP: 通过突变表型推断
18772338 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
17640331 RGD
involved in response to vitamin B3 IEP
IEP: 通过表达模式推断
19878707 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15492479 RGD
involved in triglyceride metabolic process IMP
IMP: 通过突变表型推断
15331529 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
9315741 RGD
located in brush border membrane IDA
IDA: 通过直接分析推断
21610069 RGD
located in caveola IDA
IDA: 通过直接分析推断
12637562 RGD
located in cell surface IDA
IDA: 通过直接分析推断
10487979 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
20237389 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
12829625 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

platelet glycoprotein 4

CD36 antigen (collagen type I receptor, thrombospondin receptor)

CD36 molecule (thrombospondin receptor)

Cd36 antigen-like

GPIIIB

GPIV

PAS IV

PAS-4

adipocyte membrane protein

collagen type I receptor thrombospondin receptor

fatty acid translocase

重组 Cd36 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74302 CD36 Protein, Rat (HEK293, His) Q07969 (G30-K439) ≥95%
HY-P74303 CD36 Protein, Rat (HEK293, Fc) Q07969 (G30-K439) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd36 NCBI NCBI:948
Canis familiaris Cd36 NCBI NCBI:475931
Macaca fascicularis Cd36 NCBI NCBI:101926577
Mus musculus Cd36 NCBI NCBI:12491
Macaca mulatta Cd36 NCBI NCBI:574296