2. Gene
  3. Cd36 - CD36 molecule Gene

Cd36 - CD36 molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FAT; GPIV; Scarb3

基因 ID: 12491 | 基因类型: protein coding

关于 Cd36

功能概要

Enables lipoprotein particle binding activity; lipoteichoic acid immune receptor activity; and low-density lipoprotein particle receptor activity. Involved in several processes, including lipid transport; regulation of gene expression; and regulation of Reactive Oxygen Species metabolic process. Acts upstream of or within several processes, including phagocytosis; positive regulation of cytokine production; and response to bacterium. Located in several cellular components, including brush border membrane; external side of plasma membrane; and membrane raft. Is expressed in several structures, including Meckel's cartilage; axial skeleton; bone; hindlimb; and telencephalon. Used to study platelet-type bleeding disorder 10. Human ortholog(s) of this gene implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; pulmonary tuberculosis; and type 2 diabetes mellitus. Orthologous to human CD36 (CD36 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd36 基因产物(5)

mRNA Protein Name
NM_001159555.1 NP_001153027.1 platelet glycoprotein 4
NM_001159556.1 NP_001153028.1 platelet glycoprotein 4
NM_001159557.1 NP_001153029.1 platelet glycoprotein 4
NM_001159558.1 NP_001153030.1 platelet glycoprotein 4
NM_007643.4 NP_031669.3 platelet glycoprotein 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables high-density lipoprotein particle binding IDA
IDA: 通过直接分析推断
14729860 MGI
enables lipoteichoic acid immune receptor activity IMP
IMP: 通过突变表型推断
16061696 MGI
enables low-density lipoprotein particle binding IMP
IMP: 通过突变表型推断
10772654 MGI
enables low-density lipoprotein particle receptor activity IMP
IMP: 通过突变表型推断
10772654 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15748999 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of MAPK cascade IMP
IMP: 通过突变表型推断
15690042 MGI
involved in amyloid fibril formation IDA
IDA: 通过直接分析推断
23812099 MGI
acts upstream of or within apoptotic cell clearance IMP
IMP: 通过突变表型推断
15647754 MGI
involved in cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
20978343 MGI
acts upstream of or within cellular response to bacterial lipopeptide IMP
IMP: 通过突变表型推断
15690042 MGI
involved in cellular response to hydroperoxide IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
16061696 MGI
acts upstream of or within cellular response to lipoteichoic acid IDA
IDA: 通过直接分析推断
15690042 MGI
acts upstream of or within cellular response to lipoteichoic acid IMP
IMP: 通过突变表型推断
15690042 MGI
involved in cellular response to low-density lipoprotein particle stimulus IDA
IDA: 通过直接分析推断
23395392 MGI
involved in cellular response to oxidative stress IMP
IMP: 通过突变表型推断
20978343 MGI
involved in cholesterol import IMP
IMP: 通过突变表型推断
17507371 MGI
involved in cholesterol transport IMP
IMP: 通过突变表型推断
12376530 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: 通过突变表型推断
15690042 MGI
involved in energy homeostasis IMP
IMP: 通过突变表型推断
23557700 MGI
acts upstream of interleukin-12 production IMP
IMP: 通过突变表型推断
16061696 MGI
acts upstream of interleukin-6 production IMP
IMP: 通过突变表型推断
16061696 MGI
involved in intestinal absorption IMP
IMP: 通过突变表型推断
17507371 MGI
involved in intestinal cholesterol absorption IMP
IMP: 通过突变表型推断
17507371 MGI
involved in lipid storage IMP
IMP: 通过突变表型推断
10772654 MGI
involved in lipoprotein transport IMP
IMP: 通过突变表型推断
10772654 MGI
involved in long-chain fatty acid import into cell IMP
IMP: 通过突变表型推断
17507371 MGI
involved in low-density lipoprotein particle clearance IMP
IMP: 通过突变表型推断
10772654 MGI
involved in low-density lipoprotein particle mediated signaling IDA
IDA: 通过直接分析推断
20978343 MGI
acts upstream of macrophage cytokine production IMP
IMP: 通过突变表型推断
15690042 MGI
involved in negative regulation of angiogenesis IMP
IMP: 通过突变表型推断
10613822 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
20978343 MGI
involved in negative regulation of protein import into nucleus IMP
IMP: 通过突变表型推断
20978343 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within phagocytosis, recognition IDA
IDA: 通过直接分析推断
16061696 MGI
involved in plasma lipoprotein particle clearance IMP
IMP: 通过突变表型推断
12376530 MGI
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
21610069 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
15690042 MGI
involved in positive regulation of NLRP3 inflammasome complex assembly IDA
IDA: 通过直接分析推断
23812099 MGI
involved in positive regulation of blood coagulation IMP
IMP: 通过突变表型推断
20978343 MGI
involved in positive regulation of blood microparticle formation IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
16061696 MGI
involved in positive regulation of cholesterol storage IMP
IMP: 通过突变表型推断
12376530 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
25596128 MGI
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
18162488 MGI
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
20037584 MGI
involved in positive regulation of interleukin-1 beta production IDA
IDA: 通过直接分析推断
23812099 MGI
acts upstream of or within positive regulation of interleukin-12 production IMP
IMP: 通过突变表型推断
16061696 MGI
acts upstream of or within positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
16061696 MGI
acts upstream of or within positive regulation of macrophage cytokine production IMP
IMP: 通过突变表型推断
15690042 MGI
involved in positive regulation of macrophage derived foam cell differentiation IMP
IMP: 通过突变表型推断
10772654 MGI
involved in positive regulation of nitric oxide biosynthetic process IGI
IGI: 通过遗传相互作用推断
20037584 MGI
involved in positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
20978343 MGI
acts upstream of or within positive regulation of phagocytosis, engulfment IDA
IDA: 通过直接分析推断
16061696 MGI
acts upstream of or within positive regulation of phagocytosis, engulfment IMP
IMP: 通过突变表型推断
16061696 MGI
involved in positive regulation of reactive oxygen species biosynthetic process IMP
IMP: 通过突变表型推断
20037584 MGI
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
15690042 MGI
involved in receptor internalization IDA
IDA: 通过直接分析推断
23395392 MGI
involved in regulation of action potential IMP
IMP: 通过突变表型推断
29111364 MGI
involved in regulation of removal of superoxide radicals IMP
IMP: 通过突变表型推断
20978343 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
involved in response to fatty acid IDA
IDA: 通过直接分析推断
21610069 MGI
involved in response to fatty acid IMP
IMP: 通过突变表型推断
23557700 MGI
involved in response to linoleic acid IDA
IDA: 通过直接分析推断
18162488 MGI
involved in response to lipid IDA
IDA: 通过直接分析推断
21610069 MGI
involved in response to stilbenoid IEP
IEP: 通过表达模式推断
17086191 MGI
involved in sensory perception of taste IDA
IDA: 通过直接分析推断
18162488 MGI
involved in triglyceride transport IMP
IMP: 通过突变表型推断
17507371 MGI
acts upstream of tumor necrosis factor production IMP
IMP: 通过突变表型推断
15690042 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
15496455 MGI
located in apical part of cell IDA
IDA: 通过直接分析推断
16276419 MGI
located in brush border membrane IDA
IDA: 通过直接分析推断
21610069 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
15690042 MGI
located in membrane IDA
IDA: 通过直接分析推断
23395392 MGI
located in membrane raft IDA
IDA: 通过直接分析推断
15496455 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15496455 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

platelet glycoprotein 4

CD36 antigen

GPIIIB

PAS IV

PAS-4

fatty acid translocase

glycoprotein IIIb

platelet glycoprotein IV

重组 Cd36 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72733 CD36 Protein, Mouse (HEK293, Fc) Q08857 (G30-K439) ≥95%
HY-P72355 CD36 Protein, Mouse (Biotinylated, HEK293, Avi-His) Q08857 (G30-K439) ≥95%
HY-P72894 CD36 Protein, Mouse (HEK293, His-Fc) Q08857 (G30-K439) ≥95%
HY-P72895 CD36 Protein, Mouse (HEK293, His) Q08857 (G30-K439) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-155938 Cyano-myracrylamide Inhibitor / Phase 3
Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112847A Sulfosuccinimidyl oleate sodium Inhibitor ≥98.0% 否
HY-163541 SMS121 Inhibitor 98.75% 否
HY-P3970A KRFK TFA Agonist 99.90% 否
HY-126726 KOdiA-PC ≥99.0% 否
HY-128671 6-​Thioinosine 98.82% 否
HY-116003 12,13-DiHOME ≥99.0% 否
HY-112847 Sulfosuccinimidyl oleate Inhibitor / 否
HY-154857 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine Ligand / 否
HY-P10388 TAX2 peptide / 否
HY-RS02237 CD36 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-125554 KDdiA-PC / 否
HY-163649 A17 Activator / 否
HY-168049 ZLY06 Agonist / 否
HY-168371 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC / 否
HY-P3970 KRFK Agonist / 否
HY-112847B (E/Z)-Sulfosuccinimidyl oleate sodium / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990352 Anti-CD36 Antibody Inhibitor / 否
HY-P990353 Anti-CD4 Antibody (TRX1) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd36 NCBI NCBI:948
Canis familiaris Cd36 NCBI NCBI:475931
Macaca fascicularis Cd36 NCBI NCBI:101926577
Rattus norvegicus Cd36 NCBI NCBI:29184
Macaca mulatta Cd36 NCBI NCBI:574296
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