2. Gene
  3. NRBP1 - nuclear receptor binding protein 1 Gene

NRBP1 - nuclear receptor binding protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核受体结合蛋白 1

种属: Homo sapiens

同用名: MADM; NRBP; BCON3; MUDPNP

基因 ID: 29959 | 基因类型: protein coding

关于 NRBP1

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:27,427,790-27,442,259 (from NCBI)

This gene has 9 transcripts (splice variants), 272 orthologues and 6 paralogues. Ubiquitous expression in esophagus (RPKM 41.1), testis (RPKM 38.5) and 25 other tissues.

功能概要

预测可实现蛋白质同源二聚化活性。参与内质网向高尔基体小泡介导的转运。位于内膜系统。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein homodimerization activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endomembrane system. [provided by Alliance of Genome Resources, Apr 2022]

NRBP1 基因产物(7)

mRNA Protein Name
NM_001321357.2 NP_001308286.1 nuclear receptor-binding protein isoform 1
NM_001321358.2 NP_001308287.1 nuclear receptor-binding protein isoform 2
NM_001321359.2 NP_001308288.1 nuclear receptor-binding protein isoform 2
NM_001321361.2 NP_001308290.1 nuclear receptor-binding protein isoform 3
NM_001321362.2 NP_001308291.1 nuclear receptor-binding protein isoform 4
NM_001321363.2 NP_001308292.1 nuclear receptor-binding protein isoform 5
NM_013392.4 NP_037524.1 nuclear receptor-binding protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11956649 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endoplasmic reticulum to Golgi vesicle-mediated transport IDA
IDA: 通过直接分析推断
11956649 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endomembrane system IDA
IDA: 通过直接分析推断
11956649 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NRBP1 蛋白结构

Pkinase

Pkinase: Protein kinase domain (83 - 325)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 535 a.a.
蛋白主名 其他名称

nuclear receptor-binding protein

multiple domain putative nuclear protein

NRBP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q8IV54
Y2H Prey Pooling
25416956
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q8IV54
Validated Y2H
25416956
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q8IV54
Y2H Array
25416956
Intra NRBP1 Q9UHY1 C2orf50 Homo sapiens Q96LR7
Y2H Prey Pooling
32296183
Intra NRBP1 Q9UHY1 C2orf50 Homo sapiens Q96LR7
Y2H Array
32296183
Intra NRBP1 Q9UHY1 SNX31 Homo sapiens Q8N9S9-2
Y2H Array
32296183
Intra NRBP1 Q9UHY1 SNX31 Homo sapiens Q8N9S9-2
Y2H Prey Pooling
32296183
Cross NRBP1 Q9UHY1 Sall4 Mus musculus Q8BX22
Anti Tag CoIP
22510880
Cross NRBP1 Q9UHY1 Sall4 Mus musculus Q8BX22
TAP
22510880
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q9Y3Q8
Y2H Pooling
16189514
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q9Y3Q8
MAPPIT
25416956
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q9Y3Q8
Pull Down
32707033
Intra NRBP1 Q9UHY1 TSC22D4 Homo sapiens Q9Y3Q8
Anti Tag CoIP
35271311
Intra NRBP1 Q9UHY1 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
32296183
Intra NRBP1 Q9UHY1 SORBS3 Homo sapiens O60504
Y2H Array
32296183
Intra NRBP1 Q9UHY1 RAC3 Homo sapiens P60763
IF
11956649
Intra NRBP1 Q9UHY1 RAC3 Homo sapiens P60763
Y2H
11956649
Cross NRBP1 Q9UHY1 polg_den2n Dengue virus type 2 P14340
Anti Tag CoIP
15084397
Cross NRBP1 Q9UHY1 polg_den2n Dengue virus type 2 P14340
Y2H
15084397
Cross NRBP1 Q9UHY1 polg_den2n Dengue virus type 2 P14340
Imaging
15084397
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Dengue Virus

Dengue Virus, Susceptibility To

Dengue Fever, Protection Against

Dengue Fever
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09562 NRBP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus NRBP1 MGD MGI:2183436
Bos taurus NRBP1 VGNC VGNC:32255
Canis familiaris NRBP1 VGNC VGNC:43961
Rattus norvegicus NRBP1 RGD RGD:1589575
Felis catus NRBP1 VGNC VGNC:68561
Macaca mulatta NRBP1 VGNC VGNC:75524
Others NRBP1 NCBI
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